L-Leucine increases the daily body temperature and affords thermotolerance in broiler chicks.
L-Leucine increases the daily body temperature and affords thermotolerance in broiler chicks.
复制标题
L-亮氨酸会增加每日体温，并提供肉鸡小鸡的耐热性。
DOI：
10.5713/ajas.18.0677
复制
发表时间：
2019-06
期刊：
影响因子：
--
通讯作者：
Chowdhury VS
中科院分区：
文献类型：
--
作者：
Han G;Yang H;Wang Y;Haraguchi S;Miyazaki T;Bungo T;Tashiro K;Furuse M;Chowdhury VS
热应激对家禽生产构成越来越大的威胁。已经发现一些氨基酸在提供耐热性中起关键作用。近年来，研究发现，蛋内注射L-亮氨酸（L-Leu）可改变热暴露肉鸡的氨基酸代谢，提高其耐热性。在这项研究中，两种剂量（35和70 μmol/蛋）的L-Leu在胚胎第7天在卵内给药，以确定其对直肠温度（RT），体重（BW）和甲状腺激素在孵化时的影响。同时分析了出壳后雏鸡的RT、BW和耐热性的变化。结果发现，在卵内施用L-Leu剂量依赖性地降低RT和血浆甲状腺素（T4）水平刚孵化后。然而，在孵化后的新生肉鸡中，卵内给予较高剂量的L-Leu显著增加RT而不影响BW增益。在暴露于热应激的雏鸡中，与在相同的高环境温度（HT：35°C±1°C，120 min）下的对照雏鸡相比，通过卵内施用L-Leu（高剂量）显著降低RT。高剂量L-Leu的卵内给药有助于提高新生肉仔鸡在高温下的每日体温，并提供耐热性。
Heat stress poses an increasing threat for poultry production. Some amino acids have been found to play critical roles in affording thermotolerance. Recently, it was found that in ovo administration of L-leucine (L-Leu) altered amino acid metabolism and afforded thermotolerance in heat-exposed broiler chicks. In this study, two doses (35 and 70 μmol/egg) of L-Leu were administered in ovo on embryonic day 7 to determine their effect on rectal temperature (RT), body weight (BW) and thyroid hormones at hatching. Changes in RT, BW, and thermotolerance in post-hatched chicks were also analyzed. It was found that in ovo administration of L-Leu dose-dependently reduced RT and plasma thyroxine (T4) level just after hatching. In post-hatched neonatal broiler chicks, however, the higher dose of L-Leu administered in ovo significantly increased RT without affecting BW gain. In chicks that had been exposed to heat stress, the RT was significantly lowered by in ovo administration of L-Leu (high dose) in comparison with the control chicks under the same high ambient temperature (HT: 35°C±1°C, 120 min). In ovo administration of L-Leu in a high dose contributed to an increased daily body temperature and afforded thermotolerance under HT in neonatal broiler chicks.