Chest CT score in COVID-19 patients: correlation with disease severity and short-term prognosis
Chest CT score in COVID-19 patients: correlation with disease severity and short-term prognosis
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DOI：
10.1007/s00330-020-07033-y
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发表时间：
2020-07-04
影响因子：
5.9
通讯作者：
Catalano, Carlo
中科院分区：
文献类型：
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作者：
Francone, Marco;Iafrate, Franco;Catalano, Carlo
目的将基于CT的COVID-19肺炎肺部受累半定量评分与疾病的临床分期和实验室检查结果相关联。我们还旨在研究CT结果是否可以预测患者的预后。方法回顾性分析2020年3月6日至3月22日收治的130例有症状的SARS-CoV-2患者的胸部CT检查结果。根据肺叶受累程度计算半定量CT评分（0：0%; 1：< 5%; 2：5-25%; 3：26-50%; 4：51-75%; 5：> 75%;范围0-5;总体评分0-25）。数据与临床分期和实验室检查结果相匹配。生存曲线和单变量和多变量分析进行评估的作用，CT评分作为一个预测患者的结果。结果早期以磨玻璃影为主，
Objectives To correlate a CT-based semi-quantitative score of pulmonary involvement in COVID-19 pneumonia with clinical staging of disease and laboratory findings. We also aimed to investigate whether CT findings may be predictive of patients' outcome. Methods From March 6 to March 22, 2020, 130 symptomatic SARS-CoV-2 patients were enrolled for this single-center analysis and chest CT examinations were retrospectively evaluated. A semi-quantitative CT score was calculated based on the extent of lobar involvement (0:0%; 1, < 5%; 2:5-25%; 3:26-50%; 4:51-75%; 5, > 75%; range 0-5; global score 0-25). Data were matched with clinical stages and laboratory findings. Survival curves and univariate and multivariate analyses were performed to evaluate the role of CT score as a predictor of patients' outcome. Results Ground glass opacities were predominant in early-phase (