Inhibitory influences on hypoglossal neural activity by stimulation of midpontine dorsal tegmentum in decerebrate cat
Inhibitory influences on hypoglossal neural activity by stimulation of midpontine dorsal tegmentum in decerebrate cat
复制标题
去大脑猫刺激桥中背被盖对舌下神经活动的抑制作用
DOI：
10.1016/0006-8993(89)91351-6
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发表时间：
1989
期刊：
影响因子：
2.9
通讯作者：
Y. Miyamoto
中科院分区：
文献类型：
--
作者：
K. Kawahara;Y. Nakazono;S. Kumagai;Y. Yamauchi;Y. Miyamoto
在自发呼吸去大脑猫模型上，分析了刺激桥中背被盖(DTF区)对舌下神经活动和横隔肌活动的抑制作用的特点。刺激同时降低舌下神经和横隔肌的活动。但对上述两种酶活性的抑制作用在本质上是不同的。曾经被刺激抑制的横隔膜活动，在持续刺激的情况下，恢复并逐渐变大。相反，DTF刺激抑制了舌下神经的紧张性放电，紧张性神经活动的降低在刺激结束后持续存在。曾经被刺激抑制的节律性舌下活动，在DTF刺激过程中重新出现。然而，这种节律性活动在刺激终止后消失，尽管节律性横隔膜活动没有。
In the spontaneously breathing decerebrate cat, the properties of the suppressive effects on hypoglossal nerve activity and on diaphragmatic activity elicited by stimulation of the midpontine dorsal tegmentum (DTF area) were analyzed. Stimulation simultaneously decreased the activities of the hypoglossal nerve as well as that of the diaphragm. However, the inhibitory influences on the above two kinds of activities were different in nature. Diaphragmatic activity, once suppressed by stimulation, recovered and gradually became greater in amplitude in spite of the continuation of stimulation. In contrast, DTF stimulation depressed tonic discharges of the hypoglossal nerve, and the decreased tonic nerve activity persisted after stimulation ended. Rhythmic hypoglossal activity, once suppressed by stimulation, reappeared during DTF stimulation. Such a rhythmic activity, however, vanished after the termination of stimulation, although the rhythmic diaphragmatic activity did not.