Brain atrophy and intellectual impairment in heavy drinkers--a clinical, psychometric and computerized tomography study.
Brain atrophy and intellectual impairment in heavy drinkers--a clinical, psychometric and computerized tomography study.
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酗酒者的脑萎缩和智力障碍——一项临床、心理测量和计算机断层扫描研究。
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
B. Wiley
中科院分区：
文献类型：
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作者：
L. Cala;B. Jones;F. Mastaglia;B. Wiley
通过计算机断层扫描 (CT) 评估了 26 名酗酒者的大脑和小脑萎缩频率。研究结果与临床缺陷、使用韦克斯勒成人智力量表（WAIS）进行的心理测试结果以及酗酒史和营养状况相关。 19例（73%）出现脑萎缩，其中16例同时伴有小脑萎缩。大脑半球萎缩程度与年龄、饮酒史长短有较好的相关性，但神经功能缺损与萎缩的相关性较差。在 18 名受试者中发现的 WAIS 的特征模式是视觉空间和视觉运动功能受损，但其他非优势半球功能和语言技能不受影响；四种表现出智力功能的更全面的抑制。大脑半球萎缩程度与非优势半球功能损害显着相关，但与总智商无关。
The frequency of cerebral and cerebellar atrophy was assessed by computerized tomography (CT) in 26 heavy drinkers. Findings were correlated with clinical deficits, with the results of psychometric testing using the Wechsler Adult Intelligence Scale (WAIS), and with the alcoholic history and nutritional status. Cerebral atrophy was present in 19 cases (73%), 16 of whom also had cerebellar atrophy. There was a good correlation between the degree of cerebral hemisphere atrophy and age and length of drinking history, but a poor correlation between neurological deficits and atrophy. Impairment of visuo-spatial and visuo-motor functions with sparing of other non-dominant hemisphere functions and of verbal skills was the characteristic pattern found with the WAIS in 18 subjects; four showed a more global depression of intellectual function. The degree of cerebral hemisphere atrophy correlated significantly with the impairment of non-dominant hemisphere functions but not with total IQ.