Toxicity of fipronil to susceptible and resistant strains of German cockroaches (Dictyoptera: Blattellidae) and house flies (Diptera: Muscidae)
Toxicity of fipronil to susceptible and resistant strains of German cockroaches (Dictyoptera: Blattellidae) and house flies (Diptera: Muscidae)
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DOI：
10.1093/jee/90.5.1152
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发表时间：
1997-10-01
影响因子：
2.2
通讯作者：
Wen, ZM
中科院分区：
文献类型：
--
作者：
Scott, JG;Wen, ZM
在P450单加氧酶抑制剂胡椒基丁醚(PBO)存在或不存在的情况下，评价了氟虫腈对几种敏感和抗性品系的德国蟑螂和家蝇的毒力。根据72hLD50值测定，锐劲特对德国蟑螂具有较高的毒性，而PBO对其毒性影响不大。Cld-R菌株对狄氏剂的耐药性是17,000倍，与敏感菌株相比，对氟虫腈的交叉耐药性是6.7至7.7倍。这种交叉抗性不受PBO的影响。氟虫腈对其他6个品系的德国蟑螂的LD50值为
The toxicity of fipronil, a promising new insecticide, was evaluated against several susceptible and resistant strains of German cockroach and house fly in the presence or absence of the P450 monooxygenase inhibitor piperonyl butoxide (PBO). Fipronil was highly toxic to German cockroaches based on 72-h LD50 values and PBO had little effect on the toxicity. The Cld-R strain, which has >17,000-fold resistance to dieldrin, was 6.7- to 7.7-fold cross-resistant to fipronil compared with the susceptible strains. This cross-resistance was not effected by PBO. The fipronil LD50 values in 6 other strains of German cockroaches were