Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice.
Data on thrombotic ischemic lesions in the presence or absence of amyloid ß-protein precursor or its homolog amyloid precursor-like protein-2 in mice.
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DOI：
10.1016/j.dib.2015.11.050
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发表时间：
2016-03
期刊：
影响因子：
1.2
通讯作者：
Van Nostrand WE
中科院分区：
文献类型：
--
作者：
Xu F;Van Nostrand WE
淀粉样β蛋白前体（A β PP）和淀粉样β蛋白样蛋白-2（APLP 2）是血栓形成的有效抑制剂，参见相关文章“淀粉样β蛋白及其前体在调节脑血栓形成中的影响”（货车Nostrand，2016）。数据显示的是野生型小鼠、A β PP −/−小鼠和APLP 2 −/−小鼠中光诱导血栓性缺血性中风的图像，计算的梗死体积分别显示出与野生型小鼠相比约40%和33%的脑梗死。
Amyloid ß-protein precursor (AßPP) and amyloid precursor-like protein-2 (APLP2) are potent inhibitors of thrombosis, see related article “The influence of the amyloid ß-protein and its precursor in modulating cerebral thrombosis” (Van Nostrand, 2016). Datapresented are images of photo-induced thrombotic ischemic stroke in wild-type mice, AßPP−/− mice and APLP2−/− mice, and the calculated infarct volume show approximately 40% and 33%, respectively, larger cerebral infarcts compared to wild-type mice.