Frequency and predictors of suboptimal glycemic control in an African diabetic population

Frequency and predictors of suboptimal glycemic control in an African diabetic population
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DOI:
10.2147/ijgm.s124548
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发表时间:
2017-01-01
影响因子:
2.3
通讯作者:
Lumu, William
Lumu, William
中科院分区:
医学4区
文献类型:
--
作者:
Kibirige, Davis;Akabwai, George Patrick;Lumu, William

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Background: Persistent suboptimal glycemic control is invariably associated with onset and progression of acute and chronic diabetic complications in diabetic patients. In Uganda, studies documenting the magnitude and predictors of suboptimal glycemic control in adult ambulatory diabetic patients are limited. This study aimed at determining the frequency and predictors of suboptimal glycemic control in adult diabetic patients attending three urban outpatient diabetic clinics in Uganda.Methods: In this hospital-based cross-sectional study, eligible ambulatory adult diabetic patients attending outpatient diabetic clinics of three urban hospitals were consecutively enrolled over 11 months. Suboptimal glycemic control was defined as glycated hemoglobin (HbA(1c)) level >= 7%. Multivariable analysis was applied to determine the predictors.Results: The mean age of the study participants was 52.2 +/- 14.4 years, and the majority of them were females (283, 66.9%). The median (interquartile range) HbA(1c) level was 9% (6.8%-12.4%). Suboptimal glycemic control was noted in 311 study participants, accounting for 73.52% of the participants. HbA(1c) levels of 7%-8%, 8.1%-9.9%, and >= 10% were noted in 56 (13.24%), 76 (17.97%), and 179 (42.32%) study participants, respectively. The documented predictors of suboptimal glycemic control were metformin monotherapy (odds ratio: 0.36, 95% confidence interval: 0.21-0.63, p