COMPARISON OF HUMAN ROTAVIRUS DISEASE IN TROPICAL AND TEMPERATE SETTINGS
COMPARISON OF HUMAN ROTAVIRUS DISEASE IN TROPICAL AND TEMPERATE SETTINGS
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DOI：
10.1001/archpedi.1978.02120340029004
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发表时间：
1978-01-01
影响因子：
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通讯作者：
MOHS, E
中科院分区：
文献类型：
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作者：
HIEBER, JP;SHELTON, S;MOHS, E
人轮状病毒（HRV）是小儿急性非细菌性胃肠炎的常见病因。一项在温带（达拉斯）[德克萨斯州，美国]和热带（圣何塞，哥斯达黎加）环境中进行的HRV疾病的前瞻性研究显示了季节分布的差异。在这两个地区，从12月到2月，HRV占急性非细菌性胃肠炎发作的50%到60%;这一时期对应于达拉斯冬季较冷的月份和圣何塞的旱季。在观察年的其余时间里，没有从任何达拉斯患者身上发现病毒，但除5月外，每个月都在30-40%的哥斯达黎加患者身上发现病毒。体征、症状和实验室检查值表明小肠是病理生理学的主要部位;某些病例可能发生粘膜破坏。
Human rotaviruses (HRV) are a common cause of acute nonbacterial gastroenteritis in pediatric patients. A prospective study of HRV disease in a temperate (Dallas) [Texas, USA] and a tropical (San Jose, Costa Rica) setting demonstrated differences in seasonal distribution. In both locales, HRV accounted for 50% to 60% of acute nonbacterial gast-oenteritis episodes from Dec. through Feb.; this period corresponded to the cooler months of winter in Dallas and to the dry season in San Jose. During the rest of the observation year, the virus was not recovered from any Dallas patients, but was found in 30-40% of Costa Rican patients in every month but May. Signs, symptoms and laboratory values suggest the small bowel as the major site of pathophysiology; mucosal disruption may occur in some cases.