Site-selective depurination by a periodate-dependent deoxyribozyme

Site-selective depurination by a periodate-dependent deoxyribozyme
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DOI:
10.1039/b704507g
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发表时间:
2007-06-14
影响因子:
4.9
通讯作者:
Silverman, Scott K.
Silverman, Scott K.
中科院分区:
化学2区
文献类型:
--
作者:
Hobartner, Claudia;Pradeepkumar, P. I.;Silverman, Scott K.

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鉴定了一种脱氧核酶,其使用高碘酸盐(IO 4-)作为强制性辅因子介导其5 '-末端鸟苷核苷酸的位点选择性脱嘌呤。
A deoxyribozyme is identified that mediates the site-selective depurination of its 5'-terminal guanosine nucleotide using periodate (IO4-) as an obligatory cofactor.