Anhedonia and emotional word memory in patients with depression
Anhedonia and emotional word memory in patients with depression
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DOI：
10.1016/j.psychres.2012.07.025
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发表时间：
2012-12-30
影响因子：
11.3
通讯作者：
Chan, Raymond C. K.
中科院分区：
文献类型：
--
作者：
Liu, Wen-hua;Wang, Ling-zhi;Chan, Raymond C. K.
快感缺乏是诊断重性抑郁症的一个关键标准。探讨特定症状与情绪处理之间的关系可能有助于了解抑郁症快感缺失的潜在认知机制。在这项研究中，我们探讨了71名抑郁症患者和61名健康人的情绪词记忆和快感缺乏之间的潜在联系。一个情绪字评级任务，以评估自我报告的情绪体验的价格和唤醒的尺寸，以及随后的回忆和识别这些话的记忆。抑郁症患者表现出减少的快乐和唤醒经验，积极的话，但增加唤醒经验，消极的话。抑郁症患者在回忆测量中也表现出较低的整体记忆表现，并且偏向于记忆更多的负面词汇。此外，只有抑郁症患者的状态性快感缺失和特质性快感缺失与减弱的积极体验和增强的消极体验相关。高水平的快感缺失和抑郁严重程度也与较少的积极词汇和更多的消极词汇记忆有关。抑郁症患者对积极刺激的情绪体验呈现出平坦的模式，对消极刺激的评价更强烈。(C)2012爱思唯尔爱尔兰有限公司保留所有权利。
Anhedonia is a key diagnostic criterion for major depression. Investigating the relation between the specific symptoms and emotional processing may help to understand the underlying cognitive mechanism of anhedonia in depression. In this study, we explored the potential association between memory for emotional words and anhedonia in 71 patients with depression and 61 healthy individuals. An emotional word-rating task was administered to assess self-reported emotional experience to words on both valence and arousal dimensions, and subsequent recall and recognition memory for these words. Depressed patients demonstrated a reduction in pleasure and arousal experience to positive words, but an increase in arousal experience to negative words. Depressed patients also displayed a lower overall memory performance in recall measure and a bias to memory of more negative words. Moreover, state anhedonia and trait anhedonia were associated with attenuated positive experience and enhanced negative experience in patients with depression only. Higher levels of anhedonia and depression severity were also associated with fewer positive words and more negative words memory. Patients with depression displayed a flat pattern of emotional experience to positive stimuli and a tendency towards rating negative stimuli more intensely. (C) 2012 Elsevier Ireland Ltd. All rights reserved.