Inflammation imaging in atherosclerosis.

Inflammation imaging in atherosclerosis.
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DOI:
10.1161/atvbaha.108.165563
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发表时间:
2009-07
期刊:
Arteriosclerosis, thrombosis, and vascular biology
影响因子:
--
通讯作者:
Fayad ZA
Fayad ZA
中科院分区:
其他
文献类型:
--
作者:
Rudd JH;Hyafil F;Fayad ZA

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炎症在动脉粥样硬化斑块发展的许多阶段都很重要。我们强调了几种成像方式,可以量化斑块炎症程度的非侵入性。这种类型的成像可能允许测试新的抗动脉粥样硬化药物,识别有斑块破裂风险的患者,并更深入地了解疾病的生物学。成像方式进行了讨论,在这些领域的潜在用途。
Inflammation is important at many stages of atherosclerotic plaque development. We highlight several imaging modalities that can quantify the degree of plaque inflammation noninvasively. Imaging of this type might allow testing of novel antiatherosclerosis drugs, identification of patients at risk of plaque rupture, and deeper insight into the biology of the disease. The imaging modalities are discussed in relation to their potential use in these areas.