QUANTITATIVE BACTERIOLOGY OF AMNIOTIC-FLUID FROM WOMEN WITH CLINICAL INTRA-AMNIOTIC INFECTION AT TERM

QUANTITATIVE BACTERIOLOGY OF AMNIOTIC-FLUID FROM WOMEN WITH CLINICAL INTRA-AMNIOTIC INFECTION AT TERM
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DOI:
10.1093/infdis/145.1.1
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发表时间:
1982-01-01
影响因子:
6.4
通讯作者:
CASTANEDA, YS
CASTANEDA, YS
中科院分区:
医学2区
文献类型:
--
作者:
GIBBS, RS;BLANCO, JD;CASTANEDA, YS

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通过宫内导管从 52 名患有临床羊膜内感染的女性和 52 名未感染的匹配对照女性中收集羊水。定量培养羊水中的厌氧菌和需氧菌。根据胎龄、胎膜破裂至标本采集的时间间隔以及胎膜破裂至分娩的时间间隔,将羊膜内感染患者与对照妇女进行匹配。羊膜内感染患者的平均体温明显较高(38.4 摄氏度 vs. 37.1 摄氏度),平均白细胞计数也较高(15,740 个细胞/mm3 vs. 11,740 个细胞/mm3)。 80.6% 的羊膜内感染女性样本和 30.8% 的对照受试者样本中存在 .gtoreq。从羊水中分离出 102 个菌落形成单位 (cfu)/ml (P < 0.001)。此外,前者的 69.2% 和后者的 7.7% 中,每毫升有 > 102 cfu 的菌株被认为是高毒力菌株(P < 0.001)。
Amniotic fluid was collected through an intrauterine catheter from 52 women with clinical intraamniotic infection and from 52 uninfected matched control women. The amniotic fluid was cultured quantitatively for anaerobes and aerobes. Patients with intraamniotic infection were matched with the control women on the basis of gestational age, interval from membrane rupture to specimen collection and interval from membrane rupture to delivery. The patients with intraamniotic infection had a significantly higher mean temperature (38.4 vs. 37.1.degree. C) and a higher mean leukocyte count (15,740 vs. 11,740 cells/mm3). In 80.6% of specimens from the women with intraamniotic infection and 30.8% of those from the control subjects, .gtoreq. 102 colony-forming units (cfu)/ml were isolated from the amniotic fluid (P < 0.001). Also, in 69.2% of the former and 7.7% of the latter, there were > 102 cfu of isolates considered to be high-virulence isolates/ml (P < 0.001).