Plasma-etched neural probes

Plasma-etched neural probes
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DOI:
10.1016/s0924-4247(97)80221-x
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发表时间:
1997-01-01
影响因子:
4.6
通讯作者:
Kovacs, GTA
Kovacs, GTA
中科院分区:
工程技术3区
文献类型:
--
作者:
Kewley, DT;Hills, MD;Kovacs, GTA

文献摘要

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提出了一种用于神经生物学研究的硅基神经探针微加工的新方法。这种探针提供了独特的能力,可以同时记录来自神经组织内多个精确定义位置的高分辨率信号。制造过程利用等离子体蚀刻来定义探针轮廓,从而产生尖锐的尖端,并与标准CMOS工艺兼容。通过MOSIS服务制造了一个低噪声放大器阵列,以完成一个系统,该系统已在多个成功的生理实验中使用。
A new method is presented for microfabricating silicon-based neural probes that are designed for neurobiology research. Such probes provide unique capabilities to record high-resolution signals simultaneously from multiple, precisely defined locations within neural tissue, The fabrication process utilizes a plasma etch to define the probe outline, resulting in sharp tips and compatibility with standard CMOS processes, A low-noise amplifier array has been fabricated through the MOSIS service to complete a system that has been used in multiple successful physiological experiments.