Dectin-1 Exerts Dual Control in the Gut.
Dectin-1 Exerts Dual Control in the Gut.
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DOI:
10.1016/j.chom.2015.07.010
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发表时间:
2015-08-12
影响因子:
30.3
通讯作者:
Iliev ID
中科院分区:
文献类型:
--
作者:
Iliev ID
Dectin-1, a β-glucan receptor, contributes to host anti-fungal defense. In this issue of Cell Host & Microbe, Tang et al show that suppressing Dectin-1 signaling protects mice from experimental colitis by decreasing anti-microbial peptide production, which allows overgrowth of Lactobacilli and triggers T regulatory cell expansion in the gut.