Antimalarial bednet protection of children disappears when shared by three or more people in a high transmission setting of western Kenya
Antimalarial bednet protection of children disappears when shared by three or more people in a high transmission setting of western Kenya
复制标题
在肯尼亚西部高传播环境中，当三人或三人以上共用时，对儿童的抗疟蚊帐保护就会消失
DOI：
10.1017/s003118201800149x
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发表时间：
2018
期刊：
影响因子：
2.4
通讯作者：
Peter S. Larson
中科院分区：
文献类型：
--
作者：
Noriko Tamari;N. Minakawa;George O. Sonye;Beatrice Awuor;James O. Kongere;S. Munga;Peter S. Larson
相当大比例的家庭被迫共用一顶长效驱虫蚊帐。然而，越来越多的人共用蚊帐与疟原虫感染风险之间的关系尚不清楚。这项研究揭示了恶性疟原虫感染的风险是否与肯尼亚完全流行地区共用长效驱虫蚊帐的人数有关。使用聚合酶链反应检测15岁以下儿童的恶性疟原虫感染。在接受调查的558名儿童中，293名（52.5%）寄生虫病检测呈阳性。458人（82.1%）报告在LLIN下睡觉。其中，与抽样儿童共用蚊帐的人数从1人到5人不等（中位数= 2）。单独使用蚊帐或与他人一起使用蚊帐的儿童的风险低于不使用蚊帐的儿童（OR = 0.29，95%CI 0.10-0.82和OR = 0.47，95%CI 0.22-0.97）。另一方面，非使用者和儿童与两个（OR = 0.88，95%CI 0.44-1.77）或更多其他人（OR = 0.75，95%CI 0.32-1.72）共用蚊帐之间没有显著差异。与不使用长效驱虫蚊帐相比，长效驱虫蚊帐单独使用或与另一个人一起使用时可有效保护儿童免受疟原虫感染。公共卫生专业人员应告知护理人员太多人共用蚊帐的风险。
Abstract A sizeable proportion of households is forced to share single long-lasting insecticide treated net (LLIN). However, the relationship between increasing numbers of people sharing a net and the risk for Plasmodium infection is unclear. This study revealed whether risk for Plasmodium falciparum infection is associated with the number of people sharing a LLIN in a holoendemic area of Kenya. Children ⩽5 years of age were tested for P. falciparum infection using polymerase chain reaction. Of 558 children surveyed, 293 (52.5%) tested positive for parasitaemia. Four hundred and fifty-eight (82.1%) reported sleeping under a LLIN. Of those, the number of people sharing a net with the sampled child ranged from 1 to 5 (median = 2). Children using a net alone or with one other person were at lower risk than non-users (OR = 0.29, 95% CI 0.10–0.82 and OR = 0.47, 95% CI 0.22–0.97, respectively). On the other hand, there was no significant difference between non-users and children sharing a net with two (OR = 0.88, 95% CI 0.44–1.77) or more other persons (OR = 0.75, 95% CI 0.32–1.72). LLINs are effective in protecting against Plasmodium infection in children when used alone or with one other person compared with not using them. Public health professionals should inform caretakers of the risks of too many people sharing a net.