The nasotemporal division in primate retina: the neural bases of macular sparing and splitting.
The nasotemporal division in primate retina: the neural bases of macular sparing and splitting.
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DOI：
10.1126/science.3353708
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发表时间：
1988-04
期刊：
影响因子：
56.9
通讯作者：
A. Leventhal;S. Ault;D. J. Vitek
中科院分区：
文献类型：
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作者：
A. Leventhal;S. Ault;D. J. Vitek
在灵长类动物中，每个半球包含一个对侧视觉半球的代表；单侧视觉通路的损伤会导致一半视野的视力丧失。显然，类似的严重的单侧中央视觉通路病变可导致两种质量不同的中央视野缺陷，称为黄斑保留和黄斑分裂。在黄斑保留中，中央凹周围的2 - 3度区域不受单侧视觉通路损伤的影响。在黄斑分裂中，没有这样的幸免区域，单侧脑损伤产生的暗斑将中央窝一分为二。用辣根过氧化物酶注射测定了新世界猴和旧大陆猴视网膜神经节细胞不同种类的讨论模式。在这两个物种中，同侧和对侧突出的神经节细胞在视网膜中央的分布与其他哺乳动物不同，分别提示黄斑保留和分裂的神经基础。
In primates, each hemisphere contains a representation of the contralateral visual hemifield; unilateral damage to the visual pathways results in loss of vision in half of the visual field. Apparently similar severe, unilateral lesions to the central visual pathways can result in two qualitatively different central visual field defects termed macular sparing and macular splitting. In macular sparing a 2 degrees to 3 degrees region around the fovea is spared from the effects of unilateral damage to the visual pathways. In macular splitting there is no such spared region and the scotoma produced by unilateral brain damage bisects the fovea. The patterns of decussation of the different classes of retinal ganglion cells in both New World (Saimiri sciureus) and Old World (Macaca fascicularis) monkeys have been determined by horseradish peroxidase injection. In both species the distributions of ipsilaterally and contralaterally projecting ganglion cells in the central retina are different from those in other mammals and suggest neural bases for macular sparing and splitting, respectively.