A Six-Stage Workflow for Robust Application of Systems Pharmacology.
A Six-Stage Workflow for Robust Application of Systems Pharmacology.
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DOI：
10.1002/psp4.12071
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发表时间：
2016-05
期刊：
影响因子：
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通讯作者：
Ramanujan S
中科院分区：
文献类型：
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作者：
Gadkar K;Kirouac DC;Mager DE;van der Graaf PH;Ramanujan S
定量和系统药理学（QSP）越来越多地应用于药物研究和开发。快速启动方案最终成功的一个关键因素是建立普遍接受的语言、技术标准和工作流程。我们提出了一个集成的工作流程，桥梁的概念目标与底层的技术细节，以支持执行，沟通和评估的QSP项目。
Quantitative and systems pharmacology (QSP) is increasingly being applied in pharmaceutical research and development. One factor critical to the ultimate success of QSP is the establishment of commonly accepted language, technical criteria, and workflows. We propose an integrated workflow that bridges conceptual objectives with underlying technical detail to support the execution, communication, and evaluation of QSP projects.