Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity

Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity
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DOI：
10.1111/j.1442-2042.2004.00973.x
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发表时间：
2005-01
期刊：
International Journal of Urology
影响因子：
2.6
通讯作者：
H. Ouchi;H. Ishiguro;N. Ikeda;M. Hori;Y. Kubota;H. Uemura
H. Ouchi;H. Ishiguro;N. Ikeda;M. Hori;Y. Kubota;H. Uemura
中科院分区：
医学3区
文献类型：
--
作者：
H. Ouchi;H. Ishiguro;N. Ikeda;M. Hori;Y. Kubota;H. Uemura

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摘要目的：为了阐明染料木黄酮抗癌作用的机制，我们检测了染料木黄酮对前列腺癌细胞端粒酶活性的影响。我们推测染料木黄酮可能通过修饰前列腺癌细胞的端粒酶活性发挥其抗癌作用。
Abstract Aim: To clarify the mechanism of the anticancer effect of genistein, we examined the effect of genistein on telomerase activity in prostate cancer cells. We hypothesized that genistein may exert its anticancer effect by modifying telomerase activity in prostate cancer cells.