PANENCEPHALOPATHIC TYPE OF CREUTZFELDT-JAKOB DISEASE - PRIMARY INVOLVEMENT OF THE CEREBRAL WHITE MATTER

PANENCEPHALOPATHIC TYPE OF CREUTZFELDT-JAKOB DISEASE - PRIMARY INVOLVEMENT OF THE CEREBRAL WHITE MATTER
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DOI:
10.1136/jnnp.44.2.103
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发表时间:
1981-01-01
影响因子:
11
通讯作者:
SHIRAKI, H
SHIRAKI, H
中科院分区:
医学1区
文献类型:
--
作者:
MIZUTANI, T;OKUMURA, A;SHIRAKI, H

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报告了8例日本全脑型克雅氏病(CJD)的尸检病例。本文提出并强调该型与其他类型CJD分开讨论的原因:主要涉及脑白质和大脑皮层,并成功将1例与本组相似的日本人CJD脑白质病变传递给实验动物。
Eight necropsy cases of a panencephalopathic type of Creutzfeldt-Jakob disease (CJD) in the Japanese are reported. Reasons why this type should be discussed separately from other types of CJD are presented and highlighted here as follows: the cerebral white matter and cerebral cortex are primarily involved, and the white matter lesion of 1 Japanese human brain with CJD similar to the present group was successfully transmitted to experimental animals.