MATURATION OF HUMAN CEREBRUM OBSERVED INVIVO DURING ADOLESCENCE
MATURATION OF HUMAN CEREBRUM OBSERVED INVIVO DURING ADOLESCENCE
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DOI：
10.1093/brain/114.5.2037
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发表时间：
1991-10-01
期刊：
影响因子：
14.5
通讯作者：
TALLAL, PA
中科院分区：
文献类型：
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作者：
JERNIGAN, TL;TRAUNER, DA;TALLAL, PA
在本研究中，使用磁共振成像（MRI），年龄变化的大脑皮层的形态，最大的额叶和顶叶凸，在青春期观察。结果表明，增加脑脊液（CSF）内的沟，这些皮质区伴随灰质减少。在皮质下灰质核团中也观察到较小的体积减少。这些明显的灰质体积减少可能反映了大脑成熟的晚期过程。这些变化可能与神经可塑性降低有关。
In the present study using magnetic resonance imaging (MRI), age changes in the morphology of the cerebral cortex, greatest in the frontal and parietal convexities, were observed during adolescence. Results suggest that increases in cerebrospinal fluid (CSF) within the sulci of these cortical regions accompany grey matter decreases. Smaller reductions in volume are also observed in subcortical grey matter nuclei. These apparent grey matter volume reductions presumably reflect processes of late brain maturation. The changes may be related to decreasing neural plasticity.