Electronic probing of ketone catalysts for asymmetric epoxidation. Search for more robust catalysts.
Electronic probing of ketone catalysts for asymmetric epoxidation. Search for more robust catalysts.
复制标题
不对称环氧化酮催化剂的电子探测。
作者：
Tian,H;She,X;Shi,Y
合成了含稠合恶唑烷酮的酮，并研究了酮催化剂上α位取代基对Baeyer-Villiger氧化反应的电子效应和对不对称环氧化反应的催化性能.这些新的酮在催化剂含量仅为1 - 5 mol %的情况下就能得到高产率和ee。目前的研究进一步表明，电子效应对酮催化环氧化反应是非常重要的。
Ketones with a fused oxazolidinone were synthesized and investigated to determine the electronic effect of the substituents at α-positions of ketone catalysts on the Baeyer−Villiger oxidation and catalytic properties for asymmetric epoxidation. These new ketones give high yields and ee's with only 1−5 mol % catalyst. The current studies further show that the electronic effect is very important for the ketone-catalyzed epoxidation.