RegulonDB (version 3.0):: transcriptional regulation and operon organization in Escherichia coli K-12

RegulonDB (version 3.0):: transcriptional regulation and operon organization in Escherichia coli K-12
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DOI:
10.1093/nar/28.1.65
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发表时间:
2000-01-01
影响因子:
14.9
通讯作者:
Collado-Vides, J
Collado-Vides, J
中科院分区:
生物学2区
文献类型:
--
作者:
Salgado, H;Santos-Zavaleta, A;Collado-Vides, J

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RegulonDB是一个关于大肠杆菌中转录调控和操纵子组织的数据库,当前版本描述了转录起始的调控信号,启动子,特定调控因子的调控结合位点,核糖体结合位点和终止子,以及基因簇锡操纵子的信息,这些特定的注释是从文献中不断搜索收集的,以及基于计算序列预测,所有这些对象在大肠杆菌K-12染色体中的基因组坐标被清楚地指示。每个已知的对象都有一个链接到至少一个MEDLINE参考。我们还添加了与大肠杆菌K-12最近表达数据的直接链接。这里介绍的版本在数据库的结构以及数据库中编码的信息的数量和类型方面都有重要的修改。RegulonDB可通过网址http://www.cifn.unam.mx/Computational_Biology/regulondb/访问。
RegulonDB is a database on transcription regulation and operon organization in Escherichia coli, The current version describes regulatory signals of transcription initiation, promoters, regulatory binding sites of specific regulators, ribosome binding sites and terminators, as well as information on genes clustered tin operons, These specific annotations have been gathered from a constant search in the literature, as well as based on computational sequence predictions, The genomic coordinates of all these objects in the E.coli K-12 chromosome are clearly indicated. Every known object has a link to at least one MEDLINE reference. We have also added direct links to recent expression data of E.coli K-12. The version presented here has important modifications both in the structure of the database, as well as in the amount and type of information encoded in the database. RegulonDB can be accessed on the web at URL:http://www.cifn.unam.mx/Computational_Biology/regulondb/.