Otologic and audiologic evaluation of human immunodeficiency virus-infected patients
Otologic and audiologic evaluation of human immunodeficiency virus-infected patients
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DOI：
10.1016/s0196-0709(00)80117-9
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发表时间：
2000-01-01
影响因子：
2.5
通讯作者：
Baredes, S
中科院分区：
文献类型：
--
作者：
Chandrasekhar, SS;Connelly, PE;Baredes, S
目的：量化人类免疫缺陷病毒（HIV）感染者耳部疾病的发生率。材料和方法：这是一个hiv阳性患者的描述性病例系列，通过耳科问卷调查、耳科检查、听力学评估和图表回顾收集数据。这项研究是在城市大学医院的传染病和耳鼻喉科门诊进行的。连续抽取50名艾滋病毒感染者自愿参加这项研究。10名受试者拒绝了。几乎所有病人都得到公共医疗援助。描述性结果制成表格。听力测量数据分析了耳朵、疾病控制中心（CDC）组、耳科投诉和年龄影响。将数据与既定规范进行比较。结果：研究对象男性23人，女性27人，平均年龄40岁，平均HIV病程3.5年。18%的患者属于CDC-A类，38%的患者属于CDC-B类，44%的患者属于CDC-C类。耳科主诉比预期的更为普遍：34%的患者报告听力饱满，32%的患者报告头晕，29%的患者报告听力损失，26%的患者报告耳鸣，23%的患者报告耳痛，5%的患者报告耳漏。33%的患者神经耳科检查结果异常。鼓室检查有21%异常。观察到明显程度的高频感音神经性听力损失。在3个频率上，CDC-B和CDC-C患者的听力比CDC-A患者差。在除1,000 Hz外的所有频率下，抱怨听力损失的患者的耳声发射结果和听力结果明显比没有听力损失的患者差。30多岁的患者在语音频率上的听力比其他所有患者都好。结论：耳部疾病影响高达33%的hiv感染患者。中耳炎是常见病。HIV感染越严重，感音神经性听力损失越严重。耳部主诉患者有明显的耳病理。继续进行这项初步的描述工作是必要的。[J] .耳鼻喉科杂志，2000;21(1):1-9。版权所有(C) 2000由W.B.桑德斯公司)。
Purpose: To quantify the incidence of ear disease in patients infected with human immunodeficiency virus (HIV).Materials and Methods: This is a descriptive case series of HIV-positive patients, with data collected using an otologic questionnaire, otologic examination, audiologic evaluation, and chart review. The study was performed at an urban University Hospital's outpatient Infectious Disease and Otolaryngology clinics. A consecutive sample of 50 HIV-infected patients volunteered for this study. Ten subjects refused. Almost all patients received public assistance for medical care. Descriptive results were tabulated. Audiometric data were analyzed for ear, Centers for Disease Control (CDC) group, otologic complaint, and age effects. Data were compared with established norms.Results: Twenty-three men and 27 women with a mean age of 40 years and mean duration of HIV disease of 3.5 years were studied. Eighteen percent of patients were in category CDC-A, 38% in CDC-B, and 44% in CDC-C. Otologic complaints were more prevalent than expected: 34% of patients reported aural fullness, 32% dizziness, 29% hearing loss, 26% tinnitus, 23% otalgia, and 5% otorrhea. Results of the neuro-otologic examination were abnormal in 33%. Tympanometric examination was abnormal in 21%. A significant degree of high-frequency sensorineural hearing loss was observed. CDC-B and CDC-C patients had worse hearing than CDC-A patients at 3 frequencies. Patients who complained of hearing loss had significantly worse otoacoustic emission results and hearing results than patients who did not, at all frequencies except 1,000 Hz. Patients in their 30s had better hearing in the speech frequencies than did all other patients.Conclusions: Ear disease affects up to 33% of HIV-infected patients. Otitis media is a frequent finding. Sensorineural hearing loss is more severe in patients with more severe HIV infection. Patients with ear complaints have demonstrable otopathology. Continuation of this preliminary descriptive work is necessary. (Am J Otolaryngol 2000;21:1-9. Copyright (C) 2000 by W.B. Saunders Company).