Spectroscopic and pH-metric studies on the complexation of a novel tripodal amine-phenol ligand towards Al(III), Ga(III) and In(III)
Spectroscopic and pH-metric studies on the complexation of a novel tripodal amine-phenol ligand towards Al(III), Ga(III) and In(III)
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DOI：
10.1016/j.saa.2011.12.049
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发表时间：
2012-04-01
影响因子：
4.4
通讯作者：
Baral, Minati
中科院分区：
文献类型：
--
作者：
Sahoo, Suban K.;Bera, Rati Kanta;Baral, Minati
用电位法和分光光度法研究了新合成的三脚胺-酚配体顺式，顺式-1,3,5-三is{（2-羟基苄基）氨基甲基}环己烷（THAC）在离子强度为0.1 M KCI、25 +/- 1℃的水介质中对H+、Al3+、Ga3+和In3+离子的配位化学反应。确定了酚羟基的三个质子化常数，并将其作为评价金属配合物形成常数的输入数据。配体与Ga（III）、In（III）形成多种金属单体配合物MLH3、MLH2、MLH、ML、MLH-1；MLH3， ML和MLH-1与Al（III）。计算出的稳定性常数依次为Ga(III)> In(III)>Al(III)，其生理状态下的pM值均高于相应的转铁蛋白复合物。(C) 2012 Elsevier B.V.版权所有
The aqueous coordination chemistry of a newly synthesized tripodal amine-phenol ligand, cis,cis-1,3,5-tris{(2-hydroxybenzyl)aminomethyl}cyclohexane (THAC) towards H+, Al3+, Ga3+ and In3+ ions have been investigated in aqueous medium of 0.1 M KCI ionic strength and 25 +/- 1 degrees C by potentiometric and spectrophotometric methods. Three protonation constants assigned to phenolic hydroxyl groups were determined and were used as input data to evaluate the formation constants of the metal complexes. The ligand formed various monomeric metal complex species MLH3, MLH2, MLH, ML and MLH-1 with Ga(III) and In(III); MLH3, ML and MLH-1 with Al(III). The calculated stability constants followed the order Ga(III)> In(III)>Al(III), and their pM values at physiological condition were found to be higher than the corresponding transferrin complexes. (C) 2012 Elsevier B.V. All rights reserved.