Expression of protein kinase C subspecies in human leukemia‐ lymphoma cell lines
Expression of protein kinase C subspecies in human leukemia‐ lymphoma cell lines
复制标题
蛋白激酶C亚种在人白血病淋巴瘤细胞系中的表达
DOI：
10.1016/0014-5793(89)81369-9
复制
发表时间：
1989
期刊：
影响因子：
3.5
通讯作者：
Y. Nishizuka
中科院分区：
文献类型：
--
作者：
S. Sawamura;Katsuhiko Ase;N. Berry;U. Kikkawa;P. Mccaffrey;J. Minowada;Y. Nishizuka
Expression of protein kinase C (PKC) subspecies was studied in various human leukemia‐lymphoma cell lines. The PKC in most cell lines examined was resolved into two major fractions corresponding to type II (β‐sequence) and type III (α‐sequence) PKC of the rat brain. The amounts of these two subspecies greatly varied among the cell lines. Type I PKC (γ‐sequence) was expressed in none of the cell lines tested, but PKCs with undefined structures were frequently detected. The differential co‐expression of several PKC subspecies is presumably related to the state of cell differentiation.
免疫化学证据表明，在二甲亚砜和视黄酸诱导的 HL-60 分化过程中，三种蛋白激酶 C 同工酶丰度增加。
DOI：
--
发表时间：
1988
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Makowske,M;Ballester,R;Cayre,Y;Rosen,OM
通讯作者：
Rosen,OM