Spiral wave generation in heterogeneous excitable media
Spiral wave generation in heterogeneous excitable media
复制标题
DOI：
10.1103/physrevlett.88.058101
复制
发表时间：
2002-02-04
影响因子：
8.6
通讯作者：
Glass, L
中科院分区：
文献类型：
--
作者：
Bub, G;Shrier, A;Glass, L
当非均质可激介质中的耦合降低时，会出现三种不同的行为：平面波不分解传播，平面波分解成螺旋波，平面波阻挡。我们用钙敏感荧光染料在鸡胚心脏细胞单层中说明了这些现象。加入庚醇（一种减少细胞间电耦合的物质）后，我们观察到螺旋波的破裂。这些结果在一个异构元胞自动机模型中建模，其中相互作用的邻域被修改。
As the coupling in a heterogeneous excitable medium is reduced, three different types of behavior are encountered: plane waves propagate without breaking up, plane waves break up into spiral waves, and plane waves block. We illustrate these phenomena in monolayers of chick embryonic heart cells using calcium sensitive fluorescent dyes. Following the addition of heptanol, an agent that reduces the electrical coupling between cells, we observe breakup of spiral waves. These results are modeled in a heterogeneous cellular automaton model in which the neighborhood of interaction is modified.