Self-report and clinician-rated measures of depression severity: can one replace the other?
Self-report and clinician-rated measures of depression severity: can one replace the other?
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DOI：
10.1002/da.21993
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发表时间：
2012-12
影响因子：
7.4
通讯作者：
Farmer, Anne
中科院分区：
文献类型：
--
作者：
Uher, Rudolf;Perlis, Roy H.;Placentino, Anna;Dernovsek, Mojca Zvezdana;Henigsberg, Neven;Mors, Ole;Maier, Wolfgang;McGuffin, Peter;Farmer, Anne
有人认为，临床医生评定量表和自我报告问卷在抑郁症严重程度的测量中可以互换，但尚未检验当评估仅限于临床医生评定或自我报告工具时是否会丢失临床重要信息。本研究的目的是测试自我报告是否提供了临床医生评级无法获取的短期治疗结果相关信息，反之亦然。在基于基因组的抑郁症药物（GENDEP）研究中，采用临床医师评定的蒙哥马利-汉斯伯格抑郁量表（MADRS）、汉密尔顿抑郁量表（HRSD）和自我报告的贝克抑郁量表（BDI）对811例接受艾司西酞普兰或去甲替林治疗的重度抑郁症患者进行评估。在缓解抑郁症的序贯治疗替代方案（星星 *D）中，除了HRSD外，还使用临床医生评定和自我报告版本的抑郁症状快速量表（QIDS-C和QIDS-SR）对4，041例接受西酞普兰治疗的患者进行了评估。在GENDEP中，基线BDI在调整基线MADRS/HRSD后显著预测了MADRS/HRSD的结果，解释了临床医生评定结果的额外3%至4%的变化（均P <0.001）。同样，在调整基线BDI后，每个临床医生评定量表均显着预测BDI的结果，并解释了自我报告结果中额外1%的方差（均P < .001）。结果在星星 *D中得到证实，其中同一仪器的自我报告和临床医生评定版本各自对治疗结局的预测做出了独特贡献。抑郁症的完整评估应包括临床医生评定量表和自我报告的措施。
It has been suggested that clinician-rated scales and self-report questionnaires may be interchangeable in the measurement of depression severity, but it has not been tested whether clinically significant information is lost when assessment is restricted to either clinician-rated or self-report instruments. The aim of this study is to test whether self-report provides information relevant to short-term treatment outcomes that is not captured by clinician-rating and vice versa. In genome-based drugs for depression (GENDEP), 811 patients with major depressive disorder treated with escitalopram or nortriptyline were assessed with the clinician-rated Montgomery–Åsberg Depression Rating Scale (MADRS), Hamilton Rating Scale for Depression (HRSD), and the self-report Beck Depression Inventory (BDI). In sequenced treatment alternatives to relieve depression (STAR*D), 4,041 patients treated with citalopram were assessed with the clinician-rated and self-report versions of the Quick Inventory of Depressive Symptomatology (QIDS-C and QIDS-SR) in addition to HRSD. In GENDEP, baseline BDI significantly predicted outcome on MADRS/HRSD after adjusting for baseline MADRS/HRSD, explaining additional 3 to 4% of variation in the clinician-rated outcomes (both P < .001). Likewise, each clinician-rated scale significantly predicted outcome on BDI after adjusting for baseline BDI and explained additional 1% of variance in the self-reported outcome (both P < .001). The results were confirmed in STAR*D, where self-report and clinician-rated versions of the same instrument each uniquely contributed to the prediction of treatment outcome. Complete assessment of depression should include both clinician-rated scales and self-reported measures.
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影响因子：
--
作者：
Gueorguieva, R;Krystal, JH
通讯作者：
Krystal, JH
影响因子：
6.6
作者：
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DOI：
10.4088/jcp.9058tx2c
发表时间：
2011-06-01
期刊：
The Journal of clinical psychiatry
影响因子：
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作者：
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通讯作者：
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影响因子：
6.6
作者：
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影响因子：
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作者：
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通讯作者：
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