The Mouse Tumor Biology Database:: Integrated access to mouse cancer biology data

The Mouse Tumor Biology Database:: Integrated access to mouse cancer biology data
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DOI:
10.1080/01902140490495633
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发表时间:
2005-03-01
影响因子:
1.7
通讯作者:
Eppig, JT
Eppig, JT
中科院分区:
医学4区
文献类型:
--
作者:
Krupke, DM;N채f, D;Eppig, JT

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长期以来,小鼠一直被用作人类癌症研究的模型。美国国家癌症研究所在其研究领域中,包括开发新的人类癌症小鼠遗传模型和探索癌症成像作为研究工具。由于相关数据的数量和相互关联性,创建和维护小鼠肿瘤生物学的生物信息学资源对于促进当前和未来的癌症研究是必要的。小鼠肿瘤生物学(MTB)数据库提供了对遗传定义小鼠(近交系、杂交、自发和诱导突变体以及遗传工程小鼠品系)中自发和诱导肿瘤研究生成的数据的电子访问。
Mice have long been used as models for the study of human cancer The National Cancer Institute has included among its research areas of extraordinary opportunity the development of new mouse genetic models of human cancer and the exploration of cancer imaging as a research tool. Because of the volume and interconnectedness of relevant data, the creation and maintenance of bioinformatics resources for mouse tumor biology is necessary to facilitate current and future cancer research. The Mouse Tumor Biology (MTB) Database provides electronic access to data generated through the study of spontaneous and induced tumors in genetically defined mice (inbred, hybrid, spontaneous and induced mutant, and genetically engineered strains of mice).