Specific cutaneous infiltrate caused by Staphylococcus aureus in a patient with chronic myelomonocytic leukemia
Specific cutaneous infiltrate caused by Staphylococcus aureus in a patient with chronic myelomonocytic leukemia
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慢性粒单核细胞白血病患者金黄色葡萄球菌引起的特异性皮肤浸润
DOI：
10.1007/s002770000156
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发表时间：
2000
影响因子：
3.5
通讯作者：
G. Den Ottolander
中科院分区：
文献类型：
--
作者：
M. Wintzen;P. Kluin;G. Den Ottolander
我们报告一位慢性粒单核细胞白血病的病人，其表现为播散性丘疹及结节。支持皮肤白血病的论点是临床表现，病变出现和消失的周期性模式，以及组织学特征。对金黄色葡萄球菌感染给予抗生素治疗后，病变可再现。我们推测，至少在某些患者中，白血病细胞是由于局部感染而在皮肤中募集的，不仅反映了自主生长，而且反映了炎症反应。
We present a patient with chronic myelomonocytic leukemia who showed disseminated papules and nodules. Arguments in favor of leukemia cutis are the clinical appearance, the cyclic pattern with which the lesions appeared and disappeared, and the histologic features. The lesions reproducibly responded to treatment with antibiotics given for aStaphylococcus aureusinfection. We speculate that at least in some patients, leukemic cells are recruited in the skin because of local infection and do not merely reflect autonomous growth but an inflammatory response.