Isoprenoid glycerol dialkanol diethers: A series of novel archaeal lipids in marine sediments
Isoprenoid glycerol dialkanol diethers: A series of novel archaeal lipids in marine sediments
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DOI：
10.1016/j.orggeochem.2011.11.002
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发表时间：
2012-02-01
影响因子：
3
通讯作者：
Hinrichs, Kai-Uwe
中科院分区：
文献类型：
--
作者：
Liu, Xiao-Lei;Lipp, Julius S.;Hinrichs, Kai-Uwe
我们报告了一系列新的古生菌脂质，广泛存在于海洋沉积物中，并暂时指定为类异戊二烯甘油二烷醇二醚（GDDs）。它们是类异戊二烯甘油二烷基甘油四醚（GDGT）的结构类似物，其中缺少一个甘油单元，并且每个联植烷基部分具有末端OH基团。鉴别基于通过精确质量测量和质谱裂解模式解释确定的分子式。GDD-0的乙酰化证实了三个OH基团的存在，并且产物的醚裂解和还原得到两个联植烷基链。提取和酸水解的不同方案的测试表明，在样品制备过程中没有形成GDD。GDDs和GDGT在12个不同来源的海洋沉积物样品中的共存表明，在这两个醚脂池的环分布是相关的，这意味着这两个化合物类共享一个共同的生物来源。类异戊二烯GDD的存在可能与海洋沉积物中双植烷二醇的出现有关，其中GDD和二醇都可以是生物合成中间体或降解产物，并且支持最近提出的底栖古细菌的化石脂质再循环（Takano，Y.，Chikaraishi，Y.，小川，O.N.，Nomaki，H.，Morono，Y.，Inagaki，F.，Kitazato，H.，Hinrichs，K.-美国、Ohkouchi，N.，2010.深海底栖古菌对沉积膜脂的再循环。Nature Geoscience 3，858-861）。GDD核心脂质中检测到的甲烷热球菌thermolithotrophicus，这些化合物的潜在的生物学功能的培养，但没有完整的极性脂质（IPL）含有GDD作为核心脂质已被检测到。(C)2011爱思唯尔有限公司保留所有权利。
We report a new series of archaeal lipids, widespread in marine sediments and tentatively assigned as isoprenoid glycerol dialkanol diethers (GDDs). They are structural analogs of isoprenoid glycerol dialkyl glycerol tetraethers (GDGTs), with one glycerol unit missing and with each biphytanyl moiety possessing a terminal OH group. Identification is based on molecular formulae determined from accurate mass measurement and interpretation of mass spectral fragmentation patterns. Acetylation of GDD-0 confirmed the presence of three OH groups, and ether cleavage and reduction of the products afforded two biphytanyl chains. Tests of different protocols for both extraction and acid hydrolysis indicate that GDDs were not formed during sample preparation. The co-existence of GDDs and GDGTs in 12 selected marine sediment samples of varying origin showed that the ring distribution in these two ether lipid pools is related and implies that the two compound classes share a common biological source. The presence of isoprenoid GDDs is possibly linked to the occurrence of biphytane diols in marine sediments, where both GDD and diol can be either biosynthetic intermediates or degradation products, and supports the recently proposed fossil lipid recycling by benthic archaea (Takano, Y., Chikaraishi, Y., Ogawa, O.N., Nomaki, H., Morono, Y., Inagaki, F., Kitazato, H., Hinrichs, K.-U., Ohkouchi, N., 2010. Sedimentary membrane lipids recycled by deep-sea benthic archaea. Nature Geoscience 3, 858-861). GDD core lipid was detected in a culture of Methanothermococcus thermolithotrophicus, suggestive of a potential biological function for these compounds, but no intact polar lipids (IPLs) containing GDDs as core lipids have been detected to date. (C) 2011 Elsevier Ltd. All rights reserved.