Psychosocial and psychiatric risk factors for suicide - Case-control psychological autopsy study
Psychosocial and psychiatric risk factors for suicide - Case-control psychological autopsy study
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DOI：
10.1192/bjp.177.4.360
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发表时间：
2000-10-01
影响因子：
10.5
通讯作者：
Jenkins, R
中科院分区：
文献类型：
--
作者：
Cheng, ATA;Chen, THH;Jenkins, R
研究背景自杀的研究很少同时研究心理社会和精神病危险因素的个体和联合作用。目的在自杀的代表性样本中进行剂量。方法在台湾连续自杀113人和226名年龄、性别、种族和居住地区相匹配的生活对照中进行病例对照心理尸检。结果5个主要危险因素（损失事件，一级亲属的自杀行为，ICD-10重度抑郁发作，情绪不稳定的人格障碍和物质依赖）多因素条件Logistic回归分析显示，对自杀有独立影响。结论对情感性精神分裂症患者的损失事件和抑郁发作进行有效的干预和管理，有自杀行为家族倾向的不稳定受试者，通常也患有酒精或其他物质依赖，可能被证明是不同人群中预防自杀的最有效方法。
Background Few studies of suicide have simultaneously examined the individual and combined effects of psychosocial and psychiatric risk factors.Aims To dose in a representative sample of suicides.Method Acase-control psychological autopsy was conducted among 113 consecutive suicides and 226 living controls matched for age, gender, ethnicity and area of residence in Taiwan.Results Five major risk factors (loss event, suicidal behaviour in first-degree relatives, ICD-10 major depressive episode, emotionally unstable personality disorder and substance dependence) were round to have independent effects on suicide from multivariate conditional logistic regression analysis.Conclusions Effective intervention and management for loss event and major depressive episode among emotionally unstable subjects with a family tendency of suicidal behaviour, frequently also comorbid with alcohol or other substance dependence, may prove to be most effective for suicide prevention in different populations.