Depressive symptoms, alcohol use and coping drinking motives: Examining various pathways to suicide attempts among young men

Depressive symptoms, alcohol use and coping drinking motives: Examining various pathways to suicide attempts among young men
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DOI:
10.1016/j.jad.2018.02.028
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发表时间:
2018-05-01
影响因子:
6.6
通讯作者:
Gmel, Gerhard
Gmel, Gerhard
中科院分区:
医学2区
文献类型:
--
作者:
Grazioli, Veronique S.;Bagge, Courtney L.;Gmel, Gerhard

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背景:研究已经确定了几种自杀行为的相关因素,包括抑郁症状、酒精使用和应对饮酒动机。然而,它们之间的联系及其在预测自杀企图中的可能因果机制的作用尚未得到很好的理解。本研究从横向和纵向两方面考察了从饮酒、饮酒应对动机和抑郁到自杀企图的潜在途径。方法:参与者(N = 4617)是参加药物使用危险因素队列研究的年轻瑞士男性(平均年龄= 19.95)。从基线和/或15个月的随访评估中使用抑郁症状、酒精使用(每周饮酒总量、重度饮酒)和应对饮酒动机的测量来预测后续自杀企图。结果:主要发现通过抑郁症状显示间接关联,如应对饮酒动机与抑郁症状呈正相关,抑郁症状随着时间的推移与自杀企图呈正相关(对于每周饮酒总量模型,横断面模型:B = 0.130, SE = 0.035, 95% CI = 0.072, 0.207;纵向模型:B = 0.039, SE = 0.013, 95% CI = 0.019, 0.069)。酒精使用与自杀企图没有显著关系。局限性:主要局限性包括自杀企图的患病率较低,可能会降低分析中的权力效应,以及我们对酒精使用对自杀企图的远端而非近端作用的关注。结论:本研究的发现表明,有抑郁症状和/或使用酒精来应对负面影响的年轻男性可能会从针对自杀行为的项目中受益。
Background: Research has identified several correlates of suicidal behaviors including depressive symptoms, alcohol use and coping drinking motives. However, their associations and their role as possible causal mechanisms in the prediction of suicide attempt are not well understood. This study examined, both cross-sectionally and longitudinally, the potential pathways from alcohol use, drinking coping motives, and depression to suicide attempts.Methods: Participants (N = 4617) were young Swiss men (mean age = 19.95) participating in the Cohort Study on Substance Use Risk Factors. Measures of depressive symptoms, alcohol use (total drinks per week, heavy episode drinking) and coping drinking motives were used from the baseline and/or 15-month follow-up assessments to predict follow-up suicide attempt.Results: Main findings showed indirect associations through depressive symptoms, such that coping drinking motives were positively associated with depressive symptoms, which were in turn positively related to suicide attempts over time (for total drinks per week models, cross-sectional model: B = 0.130, SE = 0.035, 95% CI = 0.072, 0.207; longitudinal model: B = 0.039, SE = 0.013, 95% CI = 0.019, 0.069). Alcohol use was not significantly related to suicide attempt.Limitations: Main limitation includes a low prevalence rate for suicide attempt potentially reducing power effects in the analyses and our focus on distal-yet not proximal, role of alcohol use on suicide attempt.Conclusions: Findings of this study suggest that young men with depressive symptoms and/or those who use alcohol to cope with negative affect may benefit from programs targeting suicidal behaviors.