A vision for ubiquitous sequencing.
A vision for ubiquitous sequencing.
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DOI：
10.1101/gr.191692.115
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发表时间：
2015-10
期刊：
影响因子：
7
通讯作者：
Erlich Y
中科院分区：
文献类型：
--
作者：
Erlich Y
Genomics 最近庆祝基因组价格达到 1000 美元的里程碑，使经济实惠的 DNA 测序成为现实。随着这一目标的成功完成，测序革命的下一个目标可能是测序传感器——为实时应用而制造并以低成本大量部署的小型测序设备。本手稿的第一部分设想了一些应用程序，这些应用程序将受益于将测序仪转移到一系列领域的样本中。在第二部分中，手稿概述了为了实现无处不在的测序传感器的目标需要解决的关键障碍。
Genomics has recently celebrated reaching the $1000 genome milestone, making affordable DNA sequencing a reality. With this goal successfully completed, the next goal of the sequencing revolution can be sequencing sensors—miniaturized sequencing devices that are manufactured for real-time applications and deployed in large quantities at low costs. The first part of this manuscript envisions applications that will benefit from moving the sequencers to the samples in a range of domains. In the second part, the manuscript outlines the critical barriers that need to be addressed in order to reach the goal of ubiquitous sequencing sensors.