Repeatability and reproducibility of anterior chamber volume measurements using 3-dimensional corneal and anterior segment optical coherence tomography
Repeatability and reproducibility of anterior chamber volume measurements using 3-dimensional corneal and anterior segment optical coherence tomography
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DOI：
10.1016/j.jcrs.2010.08.053
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发表时间：
2011-03-01
影响因子：
2.8
通讯作者：
Oshika, Tetsuro
中科院分区：
文献类型：
--
作者：
Fukuda, Shinichi;Kawana, Keisuke;Oshika, Tetsuro
目的：评估使用扫源 3 维角膜和眼前段光学相干断层扫描 (CAS-OCT) 和双 Scheimpflug 成像进行前房容积 (ACV) 测量的重复性和再现性。地点：日本茨城县筑波大学临床医学研究所眼科。设计：非随机临床试验。方法：在正常眼（受试者组）和患有眼病的眼睛中进行测量。原发性闭角 (PAC)（患者组）。在受试者组中，使用 CAS-OCT 和双 Scheimpflug 成像测量整个 ACV 和中央 8.0 mm 直径的 ACV。在患者组中，使用 CAS-OCT 测量整个 ACV 和 8.0 mm ACV。计算变异系数和组内相关系数 (ICC) 以评估重复性和再现性，并评估 2 种设备之间的相关性。 结果：在受试者组中，使用 CAS-OCT 时的平均 8.0 mm ACV 为 110.14 nnm(3) +/- 12.57 (SD)，使用 Scheimpflug 成像时的平均 8.0 mm ACV 为 114.51 +/- 14.69 mm(3)；存在显着的线性相关性（r = 0.878，P < .0001）。 CAS-OCT 的平均整个 ACV 为 165.15 +/- 29.29 nnm(3)。 8.0 mm 和整个 ACV 测量的 ICC 大于 0.94。 8.0 mm ACV 和整个 ACV 测量的重复性和再现性系数小于 5%。在患者组中，8.0 mm 和整个 ACV 测量显示出良好的再现性和重复性。结论：CAS-OCT 方法允许对整个 ACV 进行无创测量，并具有足够的重复性和再现性。 CAS-OCT 和 Scheimpflug 成像的 8.0 mm ACV 测量结果具有可比性。
PURPOSE: To evaluate the repeatability and reproducibility of anterior chamber volume (ACV) measurements using swept-source 3-dimensional corneal and anterior segment optical coherence tomography (CAS-OCT) and dual Scheimpflug imaging.SETTING: Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.DESIGN: Nonrandomized clinical trial.METHODS: Measurements were taken in normal eyes (subject group) and in eyes with primary angle closure (PAC) (patient group). In the subject group, the entire ACV and the central 8.0 mm diameter ACV were measured using CAS-OCT and dual Scheimpflug imaging. In the patient group, the entire ACV and 8.0 mm ACV were measured using CAS-OCT. The coefficient of variation and intraclass correlation coefficient (ICC) were calculated to evaluate repeatability and reproducibility, and the correlation between the 2 devices was assessed.RESULTS: In the subject group, the mean 8.0 mm ACV was 110.14 nnm(3) +/- 12.57 (SD) using CAS-OCT and 114.51 +/- 14.69 mm(3) using Scheimpflug imaging; there was a significant linear correlation (r = 0.878, P < .0001). The mean entire ACV on CAS-OCT was 165.15 +/- 29.29 nnm(3). The ICCs of the 8.0 mm and entire ACV measurements were greater than 0.94. The coefficients of repeatability and reproducibility of the 8.0 mm ACV and entire ACV measurements were less than 5%. In the patient group, the 8.0 mm and entire ACV measurements showed good reproducibility and repeatability.CONCLUSIONS: The CAS-OCT method allowed noninvasive measurement of the entire ACV with sufficient repeatability and reproducibility. The 8.0 mm ACV measurements with CAS-OCT and Scheimpflug imaging were comparable.