Epidemiological characteristics of inflammatory bowel disease in North-Eastern Poland.
Epidemiological characteristics of inflammatory bowel disease in North-Eastern Poland.
复制标题
波兰东北部炎症性肠病的流行病学特征。
DOI：
10.3748/wjg.v11.i17.2630
复制
发表时间：
2005
影响因子：
4.3
通讯作者：
D. Prokopowicz
中科院分区：
文献类型：
--
作者：
A. Wiercińska;J. Jaroszewicz;R. Flisiak;D. Prokopowicz
目的
提供波兰东北部炎症性肠病（IBD）患者的临床和流行病学数据。
方法
1990年至2003年期间在比亚韦斯托克传染病科诊断和住院的248名IBD患者被纳入研究。分析年龄、性别、文化程度、工作特点、环境类型、因IBD而离职、结肠炎程度、是否需要手术治疗、是否合并其他疾病。
结果
233例IBD患者（94%）被诊断为溃疡性结肠炎（UC），只有15例（6%）被诊断为克罗恩病（CD）。CD患者在诊断时明显年轻，观察到男性占优势。UC诊断时患者的平均年龄为44.9 ± 1.1岁。患者年龄直方图呈特征性的双相分布，20 ~ 40岁和60 ~ 70岁为两个高峰。UC的主要形式是左侧结肠炎，影响了近80%的研究人群。最广泛的形式-全结肠炎存在于34例患者（15%）。只有6%的UC患者需要手术，而CD患者的手术率为36%（P<0.005）。在并存疾病中，胆石症是最常见的，在35例患者（14%）中得到证实，肺部疾病被诊断为2%，银屑病为1.4%。自1998年以来，IBD住院患者人数略有增加。
结论
在波兰，UC的发生率远高于CD。大多数UC病例诊断为年轻人（20-40岁），男性患者占主导地位。UC最常见的临床形式是左侧结肠炎。
AIM
To provide the clinical and epidemiological data of inflammatory bowel disease (IBD) patients of North-Eastern Poland.
METHODS
A total of 248 IBD patients diagnosed and hospitalized in the Department of Infectious Diseases in Bialystok between 1990 and 2003 were included in the study. We analyzed age, sex, education, characteristics of job, type of the environment, discontinuation of employment due to IBD, colitis extent, need of surgical treatment, and coexistence of other diseases.
RESULTS
Two hundred and thirty-three IBD patients (94%) were diagnosed as ulcerative colitis (UC), and only 15 (6%) were diagnosed as Crohn's disease (CD). Patients with CD were significantly younger at the time of diagnosis and male predominance was observed. The mean age of the patients at the time UC diagnosis was 44.9+/-1.1 years. Histogram of the age of patients showed the characteristic biphasic distribution with two peaks between 20 and 40 years and between 60 and 70 years. The predominant form of UC was left sided colitis, which affected almost 80% of the studied population. The most extensive form--pancolitis was present in 34 patients (15%). Only 6% of UC patients required surgery, whereas 36% of CD patients underwent surgery (P<0.005). Among coexisting disorders, cholelithiasis was the most prevalent and demonstrated in 35 patients (14%), pulmonary disorders were diagnosed in 2%, and psoriasis in 1.4%. Since 1998, the number of admitted IBD patients has slightly increased.
CONCLUSION
Occurrence of UC in Poland is much higher than that of CD. The majority of UC cases are diagnosed in young people (20-40 years) with the predominance of male patients. The most common clinical form of UC is left sided colitis.