Solubilization of Oxymatrine in Water-in-Supercritical Carbon Dioxide Microemulsions
Solubilization of Oxymatrine in Water-in-Supercritical Carbon Dioxide Microemulsions
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DOI：
10.1021/je700719r
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发表时间：
2008-06
影响因子：
--
通讯作者：
Bao-gen Su;Huabin Xing;Qilong Ren
中科院分区：
文献类型：
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作者：
Bao-gen Su;Huabin Xing;Qilong Ren
氧化苦参碱在羧酸铵全氟聚醚中的增溶量（PFPE-NH 4）水/超临界二氧化碳微乳液，其中水与表面活性剂的摩尔比为（10.2、14.8和21.0）是在（308.15、313.15、318.15、323.15和328.15）K的温度和0.822 g·mL−1的密度下，使用带有取样部分的静态装置测定的。测定的氧化苦参碱增溶量比氧化苦参碱在超临界二氧化碳中的溶解度高2个数量级，约为氧化苦参碱在本体水中溶解度的1/6 ~ 1/5。结果表明，在所有实验条件下，氧化苦参碱的增溶量均随水与表面活性剂摩尔比和温度的增加而增加。
The solubilization amount of oxymatrine in ammonium carboxylate perfluoropolyether (PFPE-NH4) water-in-supercritical carbon dioxide microemulsions with a water-to-surfactant molar ratio of (10.2, 14.8, and 21.0) was determined at temperatures of (308.15, 313.15, 318.15, 323.15, and 328.15) K and a density of 0.822 g·mL−1 using a static apparatus with a sampling part. The determined solubilization amount of oxymatrine was 2 orders of magnitude higher than the solubility of oxymatrine in supercritical carbon dioxide and about 1/6 to 1/5 of the solubility of oxymatrine in bulk water. It was indicated that the solubilization amount of oxymatrine increased with an increase of the water-to-surfactant molar ratio and temperature in all experimental conditions.