The Genetic Precursors and the Advantageous and Disadvantageous Sequelae of Inhibited Temperament: An Evolutionary Perspective
The Genetic Precursors and the Advantageous and Disadvantageous Sequelae of Inhibited Temperament: An Evolutionary Perspective
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DOI：
10.1037/a0032312
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发表时间：
2013-12-01
影响因子：
4
通讯作者：
Sturge-Apple, Melissa L.
中科院分区：
文献类型：
--
作者：
Davies, Patrick T.;Cicchetti, Dante;Sturge-Apple, Melissa L.
在进化博弈论（Korte，Koolhaas，温菲尔德，&麦克尤恩，2005）的指导下，本研究旨在确定在社会人口统计学上处于不利地位和种族多样性的样本（N = 201）中经历家庭暴力水平升高的2岁儿童中抑制气质的遗传前体和心理社会后遗症。作者采用多方法前瞻性设计，在3个年度测量场合进行了结构方程模型分析，表明多巴胺和5-羟色胺转运蛋白基因多态性唯一预测了2岁时受训练的观察者对抑制气质的评级。反过来，儿童的压抑气质通过与3岁时更大的行为灵活性相关联，间接预测了4岁时外化问题的减少。结果突出的价值，整合进化和发展的概念化，更全面地绘制发展级联抑制气质。
Guided by evolutionary game theory (Korte, Koolhaas, Wingfield, & McEwen, 2005), this study aimed to identify the genetic precursors and the psychosocial sequelae of inhibited temperament in a sociodemographically disadvantaged and racially diverse sample (N = 201) of 2-year-old children who experienced elevated levels of domestic violence. Using a multimethod, prospective design across 3 annual measurement occasions, the authors conducted structural equation modeling analyses indicating that trained observer ratings of inhibited temperament at age 2 were uniquely predicted by polymorphisms in dopamine and serotonin transporter genes. Children's inhibited temperament, in turn, indirectly predicted decreases in their externalizing problems at age 4 through its association with greater behavioral flexibility at age 3. Results highlight the value of integrating evolutionary and developmental conceptualizations in more comprehensively charting the developmental cascades of inhibited temperament.