Temporal and geographical variation in low carbon inhaler dispensing in England, 2016 to 2021: an ecological study.

Temporal and geographical variation in low carbon inhaler dispensing in England, 2016 to 2021: an ecological study.
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DOI:
10.1177/01410768221133566
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发表时间:
2023-02
影响因子:
17.3
通讯作者:
--
中科院分区:
医学2区
文献类型:
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2019-2020年,英国发布了四项国家建议,鼓励使用低碳吸入器。本研究旨在调查这些是否与英格兰初级保健配药的变化有关,并探讨地理差异与临床调试组(CCG)特征之间的关系。利用公共数据进行的生态学研究。英国所有ccg(2016年3月至2021年2月)。不适用分配的低碳吸入器百分比。2020-2021年分配的低碳吸入器比例为26.3%(880万个吸入器)。在短效β激动剂(SABA)、吸入皮质类固醇(ICS)和ICS+长效β激动剂(LABA)吸入器的研究期间,这一数字有所下降。从2019年开始,LABA和ICS+LABA+长效毒蕈碱拮抗剂吸入器也出现了同样的趋势。SABA和ICS类较少作为低碳吸入器分配(⁓6%对35-45%)。中断时间序列分析发现,2019年4月之后,SABA、LABA和ICS班级的低碳吸入器百分比略有增加,但很快就被长期趋势所抵消。此外还有地域差异,西北地区、伯明翰和伦敦一直在发放更多的低碳吸入器。CCG处方/指南中关于气候变化的建议、哮喘患病率和人口年龄分布与某些类别低碳吸入器百分比的显着变化有关。英国发放的低碳吸入器的比例仍然很低,而且还在继续下降。更多地使用低碳吸入器是可以实现的,但更有可能通过地方实施的举措来实现。
In 2019–2020, four national recommendations were published in the United Kingdom to encourage use of low carbon inhalers. This study aimed to investigate whether these were associated with a change in primary care dispensing in England and to explore associations between geographical variation and clinical commissioning group (CCG) characteristics. Ecological study using aggregated publicly available data. All CCGs in England (March 2016 to February 2021). not applicable Percentage of low carbon inhalers dispensed. The percentage of low carbon inhalers dispensed was 26.3% in 2020–2021 (of 8.8 million inhalers). This decreased over the study period for short-acting beta-agonist (SABA), inhaled corticosteroid (ICS) and ICS+long-acting beta-agonist (LABA) inhalers. The same trend was seen for LABA and ICS+LABA+long-acting muscarinic antagonist inhalers from 2019. The SABA and ICS classes were less often dispensed as low carbon inhalers (⁓6% versus 35–45%). Interrupted time series analyses found slight increases in low carbon inhaler percentage in the SABA, LABA and ICS classes after April 2019, which were soon erased by the long-term trend. There was also geographical variation, with the north-west, Birmingham and London consistently dispensing more low carbon inhalers. The presence of advice on climate change in CCG formularies/guidelines, the prevalence of asthma and population age profile were associated with significant variation in low carbon inhaler percentage for some classes. The percentage of low carbon inhalers dispensed in England remains low and continues to decrease. Greater use of low carbon inhalers is achievable, but is more likely with locally implemented initiatives.
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