Pattern of Blood Stream Infections within Neonatal Intensive Care Unit, Suez Canal University Hospital, Ismailia, Egypt.
Pattern of Blood Stream Infections within Neonatal Intensive Care Unit, Suez Canal University Hospital, Ismailia, Egypt.
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DOI：
10.1155/2014/276873
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发表时间：
2014
影响因子：
3.4
通讯作者：
Nemr NA
中科院分区：
文献类型：
--
作者：
Kishk RM;Mandour MF;Farghaly RM;Ibrahim A;Nemr NA
介绍。血流感染（BSI）是新生儿重症监护病房（NICUs）新生儿的常见问题。监测新生儿感染日益被视为安全和高质量医疗保健的重要贡献者。它导致高死亡率和严重并发症。因此，我们的目的是确定埃及苏伊士运河大学医院新生儿重症监护室脑损伤的发生率和模式，并确定其对住院、死亡率和发病率的影响。方法。本研究为前瞻性研究，纳入2013年1月至2013年6月在苏伊士运河大学医院新生儿重症监护病房入住的所有新生儿。前瞻性监测血流感染。研究了卫生保健相关感染率、死亡率、病原菌和危险因素。结果。新生儿重症监护病房共收治新生儿317例，死亡率36.0%。在本研究期间，115/317例（36.3%）出现脓毒症的临床症状，并在仅有的90例新生儿（97株）中通过血培养确诊为bsi。感染新生儿的总平均住院时间明显长于未感染新生儿（分别为34.5±18.3天和10.8±9.9天）。， P值< 0.001)。感染和未感染新生儿的总死亡率分别为38.9%和34.8%，差异有统计学意义。病原菌以克雷伯氏菌最多（27.8%），其次为假单胞菌（21.6%）和金黄色葡萄球菌（15.4%）。结论。苏伊士运河大学医院新生儿重症监护室bsi发生率较高，死亡率较高（36.0%）。
Introduction. Blood stream infection (BSI) is a common problem of newborn in neonatal intensive care units (NICUs). Monitoring neonatal infections is increasingly regarded as an important contributor to safe and high-quality healthcare. It results in high mortality rate and serious complications. So, our aim was to determine the incidence and the pattern of BSIs in the NICU of Suez Canal University Hospital, Egypt, and to determine its impact on hospitalization, mortality, and morbidity. Methods. This study was a prospective one in which all neonates admitted to the NICUs in Suez Canal University hospital between January, 2013 and June 2013 were enrolled. Blood stream infections were monitored prospectively. The health care associated infection rate, mortality rate, causative organism, and risk factors were studied. Results. A total of 317 neonates were admitted to the NICU with a mortality rate of 36.0%. During this study period, 115/317 (36.3%) developed clinical signs of sepsis and were confirmed as BSIs by blood culture in only 90 neonates with 97 isolates. The total mean length of stay was significantly longer among infected than noninfected neonates (34.5 ± 18.3 and 10.8 ± 9.9 days, resp., P value < 0.001). The overall mortality rates among infected and noninfected neonates were 38.9% and 34.8%, respectively, with a significant difference. Klebsiella spp. were the most common pathogen (27.8%) followed by Pseudomonas (21.6%) and Staphylococcus aureus (15.4%). Conclusion. The rate of BSIs in NICU at Suez Canal University Hospital was relatively high with high mortality rate (36.0%).