Predictive factors for positive diagnosis of malignant biliary strictures by transpapillary brush cytology and forceps biopsy

Predictive factors for positive diagnosis of malignant biliary strictures by transpapillary brush cytology and forceps biopsy
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DOI:
10.1111/1751-2980.12311
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发表时间:
2016-01-01
影响因子:
3.5
通讯作者:
Joh, Takashi
Joh, Takashi
中科院分区:
医学3区
文献类型:
--
作者:
Naitoh, Itaru;Nakazawa, Takahiro;Joh, Takashi

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目的内镜下经乳头刷细胞学检查和钳活检对恶性胆道狭窄(MBS)的诊断结果尚不清楚,诊断的预测因素尚未建立。我们的目的是澄清两种方法的诊断结果和预测因素。方法:我们回顾了2004年至2014年间在一个学术中心接受过经乳头刷细胞学检查(n=202)或钳活检(n=208)的241例胆道狭窄患者。结果钳活检对MBS的敏感性明显高于刷细胞学检查[60.6% (97/160)vs 36.1% (57/158)], P
ObjectiveThe diagnostic yields of endoscopic transpapillary brush cytology and forceps biopsies for malignant biliary strictures (MBS) remain unclear and predictive factors for diagnosis have not been established. We aimed to clarify the diagnostic yields of both methods and the predictive factorsMethodsWe reviewed 241 patients with biliary strictures who underwent transpapillary brush cytology (n=202) or forceps biopsy (n=208) between 2004 and 2014 at a single academic center.ResultsThe sensitivity of forceps biopsy for MBS was significantly higher than that of brush cytology [60.6% (97/160) vs 36.1% (57/158), P