Osteosarcoma: a comprehensive review.
Osteosarcoma: a comprehensive review.
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DOI：
10.1051/sicotj/2017028
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发表时间：
2018
期刊：
影响因子：
1.6
通讯作者：
Kulidjian AA
中科院分区：
文献类型：
--
作者：
Misaghi A;Goldin A;Awad M;Kulidjian AA
骨肉瘤 (OS) 是一种相对罕见的骨肿瘤，全球发病率为每年每百万人 3.4 例。在二十世纪的大部分时间里，经典操作系统的五年生存率非常低。 20 世纪 70 年代，在 OS 治疗中引入辅助化疗显着提高了生存率。本文综述了各种类型的 OS 并分析了其临床和组织学特征。我们还查阅了历史和当前文献，对诊断、分期以及治疗方法进行了简要回顾，并讨论了一些未来的治疗方向。
Osteosarcoma (OS) is a relatively rare tumor of bone with a worldwide incidence of 3.4 cases per million people per year. For most of the twentieth century, five-year survival rates for classic OS were very low. In the 1970s, the introduction of adjuvant chemotherapy in the treatment of OS increased survival rates dramatically. The current article reviews the various types of OS and analyzes the clinical and histological features. We also examine historical and current literature to present a succinct review of methods for diagnosis and staging, as well as treatment, and we also discuss some of the future directions of treatment.