Evaluation of an EMG bioimpedance measurement system for recording and analysing the pharyngeal phase of swallowing
Evaluation of an EMG bioimpedance measurement system for recording and analysing the pharyngeal phase of swallowing
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DOI：
10.1007/s00405-013-2406-3
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发表时间：
2013-07-01
影响因子：
2.6
通讯作者：
Seidl, Rainer O.
中科院分区：
文献类型：
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作者：
Schultheiss, Corinna;Schauer, Thomas;Seidl, Rainer O.
用于治疗吞咽障碍的神经假体装置需要能够真实的分析吞咽过程的定时和质量的可植入测量系统。研制了一种肌电生物阻抗（恩比）联合测量系统，并对其进行了评价。本研究作为病例对照研究进行计划和实施。Charit，柏林伦理委员会以EA 1/160/09和EA 1/161/09的投票批准了这些研究。对健康志愿者进行了调查，以检查测量的有用性和再现性，区分吞咽和头部运动的能力以及不同食物的影响。使用视频荧光透视（VFSS）检查非健康患者吞咽咽部阶段生物阻抗与解剖和功能变化之间的相关性。在1350次吞咽过程中对31名健康受试者（15 a（TM）、、16 a（TM）Euro）进行了测试，在54次吞咽过程中对19名非健康患者（17 a（TM）、、2a（TM）Euro）进行了测试。从经皮和皮下测量获得的信号曲线是相似的、特征性的和可重复的（r > 0.5），并且与使用VFSS观察到的吞咽的咽部阶段期间的解剖学和功能变化相关。头部运动与吞咽运动、食物量与吞咽量之间的差异具有统计学意义，食物的导电性、受试者的性别以及测量电极的位置对测量信号均无统计学意义。恩比能够可重复地映射吞咽的咽部相位以及与其相关的经皮和皮下变化。因此，该程序似乎适合用于对吞咽过程进行自动评估并用作植入物的组成部分。
A neuroprosthetic device for treating swallowing disorders requires an implantable measurement system capable to analysing the timing and quality of the swallowing process in real time. A combined EMG bioimpedance (EMBI) measurement system was developed and is evaluated here. The study was planned and performed as a case-control study. The studies were approved by the Charit, Berlin ethics committee in votes EA1/160/09 and EA1/161/09. Investigations were carried out on healthy volunteers in order to examine the usefulness and reproducibility of measurements, the ability to distinguish between swallowing and head movements and the effect of different food consistencies. The correlation between bioimpedance and anatomical and functional changes occurring during the pharyngeal phase of swallowing in non-healthy patients was examined using videofluoroscopy (VFSS). 31 healthy subjects (15a (TM),, 16a (TM) Euro) were tested over the course of 1350 swallows and 19 (17a (TM),, 2a (TM) Euro) non-healthy patients over the course of 54 swallows. The signal curves obtained from both transcutaneous and subcutaneous measurement were similar, characteristic and reproducible (r > 0.5) and correlated with anatomical and functional changes during the pharyngeal phase of swallowing observed using VFSS. Statistically significant differences between head movements and swallowing movements, food volumes and consistencies were found. Neither the conductivity of the food, the sex of the test subject nor the position of the measurement electrodes exerted a statistically significant effect on the measured signal. EMBI is able to reproducibly map the pharyngeal phase of swallowing and changes associated with it both transcutaneously and subcutaneously. The procedure therefore appears to be suitable for use in performing automated evaluation of the swallowing process and for use as a component of an implant.