Ultrasonographic evaluation of the calf muscle mass and architecture in elderly patients with and without sarcopenia
Ultrasonographic evaluation of the calf muscle mass and architecture in elderly patients with and without sarcopenia
复制标题
DOI：
10.1016/j.archger.2016.04.004
复制
发表时间：
2016-07-01
影响因子：
4
通讯作者：
Ozcakar, Levent
中科院分区：
文献类型：
--
作者：
Kuyumcu, Mehmet Emin;Halil, Meltem;Ozcakar, Levent
背景/目的：超声评估骨质疏松症老年受试者的肌肉质量和结构，并探讨超声测量在预测骨质疏松症中的应用。本研究人群的平均年龄为73.08+/-6.18岁。通过测量脱脂体重指数(使用生物电阻抗分析)和握力确认了骨质疏松症的诊断。测量小腿围，超声检查包括双侧腓肠肌(MG)厚度、肌束长度和羽状角；小腿皮下脂肪和真皮厚度。结果：骨质疏松症患者双侧肌肉厚度和肌束长度均显著低于对照组(P均<0.05)。骨质疏松症和非骨质疏松症受试者的羽状角度、皮下脂肪和真皮厚度相似。中位厚度比(100xt(MG)/[t(皮下组织)+t(真皮)+t(MG)])右侧为%(40~88%)，左侧为%(38~86%)。双侧腓肠肌厚度和肌束长值对预测骨质疏松症具有较高的敏感性(均为76.92%)。结论：骨质疏松症老年人腓肠肌厚度和肌束长值较低，可作为预测和量化骨质疏松症的替代指标。单独测量小腿围可能不适合用于评估骨质疏松症。取而代之的是，超声成像可以方便地用来评估(骨质疏松症)老年人肌腱系统的不同区段。(C)2016爱思唯尔爱尔兰有限公司。保留所有权利。
Background/objectives: To sonographically assess the muscle mass and architecture of sarcopenic elderly subjects, and to explore the utility of ultrasound (US) measurements in predicting sarcopenia.Methods: One hundred elderly subjects were enrolled in this cross-sectional study. Mean age value of our study population was 73.08 +/- 6.18 years. The diagnosis of sarcopenia was confirmed by measuring fat-free mass index (using bioelectrical impedance analysis) and handgrip strength. Calf circumference was measured and US evaluations comprised bilateral gastrocnemius muscle (MG) thickness, fascicle length and pennate angles; subcutaneous fat and dermis thicknesses in the calf.Results: Bilateral muscle thickness and fascicle length values were significantly lower in patients with sarcopenia (both p < 0.05). Sarcopenic and nonsarcopenic subjects had similar pennate angles, subcutaneous fat and dermis thicknesses. Median thickness ratio (100 x t (MG)/[t (subcutaneous tissue) + t (dermis) + t (MG)]) values were 64% (40-88%) in the right and 64% (38-86%) in the left calf. Bilateral MG thickness and fascicle length values showed high sensitivity in predicting sarcopenia (all values > 76.92%).Conclusions: Gastrocnemius muscle thickness and fascicle length values are lower in sarcopenic elderly and these two parameters can serve as alternative measurements for predicting/quantifying sarcopenia. Calf circumference measurements alone may not be appropriate for assessing sarcopenia. Instead, US imaging can conveniently be used to evaluate different compartments of the musculoskelal system in (sarcopenic) elderly. (C) 2016 Elsevier Ireland Ltd. All rights reserved.