PHARYNGEAL SIZE IN SNORERS, NONSNORERS, AND PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA
PHARYNGEAL SIZE IN SNORERS, NONSNORERS, AND PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA
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DOI:
10.1056/nejm198611203152105
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发表时间:
1986-11-20
影响因子:
158.5
通讯作者:
HOFFSTEIN, V
中科院分区:
文献类型:
--
作者:
BRADLEY, TD;BROWN, IG;HOFFSTEIN, V
We measured pharyngeal cross-sectional area and its change with alterations in lung volume in 10 subjects who snored and had obstructive sleep apnea, 6 subjects who snored and did not have obstructive sleep apnea, and 9 subjects who did not snore. Pharyngeal area was measured with use of an acoustic-reflection technique. We found that snorers with and without sleep apnea had a significantly smaller mean (.+-. SE) pharyngeal cross-sectional area (4.1 .+-. 0.2 and 3.7 .+-. 0.9 cm2, respectively) at functional residual capacity than nonsnorers (5.4 .+-. 0.5 cm2, P < 0.025). Whe lung volume decreased from functional residual capacity to residual volume, both nonsnoreres and snorers with sleep apnea had a decrease in pharyngeal area (from 5.4 .+-. 0.5 to 4.5 .+-. 0.4 cm2 and 4.1 .+-. 0.2 to 3.4 .+-. 0.2 cm2, respectively), whereas snorers without sleep apnea had no such decrease, suggesting that their pharynx were less collapsible at low lung volumes. We conclude that snorers with and without sleep apnea have smaller pharyngeal cross-sectional areas than nonsnorers and that snorers with sleep apnea have a further decrease as lung volume falls.