PHARYNGEAL SIZE IN SNORERS, NONSNORERS, AND PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA

PHARYNGEAL SIZE IN SNORERS, NONSNORERS, AND PATIENTS WITH OBSTRUCTIVE SLEEP-APNEA
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DOI:
10.1056/nejm198611203152105
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发表时间:
1986-11-20
影响因子:
158.5
通讯作者:
HOFFSTEIN, V
HOFFSTEIN, V
中科院分区:
医学1区
文献类型:
--
作者:
BRADLEY, TD;BROWN, IG;HOFFSTEIN, V

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我们测量了10名打鼾并患有阻塞性睡眠呼吸暂停的受试者,6名打鼾但没有阻塞性睡眠呼吸暂停的受试者,以及9名没有打鼾的受试者的咽横截面积及其随肺容量变化的变化。咽部面积的测量使用声反射技术。我们发现有和没有睡眠呼吸暂停的打鼾者的平均值(. ±. SE)咽横截面积(4.1. ±. 0.2和3.7.+-。0.9 cm2)比无打鼾者(5.4 ± 0.000cm 2)高。0.5 cm~2,P <0.025)。当肺容量从功能性残气量减少到残气量时,无打鼾者和伴有睡眠呼吸暂停的打鼾者的咽部面积都减少(从5.4 ± 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000 0.5至4.5.+-。0.4 cm~2和4.1 ±. 0.2至3.4.+-。0.2 cm 2),而无睡眠呼吸暂停的打鼾者则没有这种减少,这表明他们的咽部在低肺容量时较不容易塌陷。我们的结论是,打鼾者和无睡眠呼吸暂停有较小的咽横截面积比非打鼾者和打鼾者有睡眠呼吸暂停有进一步减少肺容量下降福尔斯。
We measured pharyngeal cross-sectional area and its change with alterations in lung volume in 10 subjects who snored and had obstructive sleep apnea, 6 subjects who snored and did not have obstructive sleep apnea, and 9 subjects who did not snore. Pharyngeal area was measured with use of an acoustic-reflection technique. We found that snorers with and without sleep apnea had a significantly smaller mean (.+-. SE) pharyngeal cross-sectional area (4.1 .+-. 0.2 and 3.7 .+-. 0.9 cm2, respectively) at functional residual capacity than nonsnorers (5.4 .+-. 0.5 cm2, P < 0.025). Whe lung volume decreased from functional residual capacity to residual volume, both nonsnoreres and snorers with sleep apnea had a decrease in pharyngeal area (from 5.4 .+-. 0.5 to 4.5 .+-. 0.4 cm2 and 4.1 .+-. 0.2 to 3.4 .+-. 0.2 cm2, respectively), whereas snorers without sleep apnea had no such decrease, suggesting that their pharynx were less collapsible at low lung volumes. We conclude that snorers with and without sleep apnea have smaller pharyngeal cross-sectional areas than nonsnorers and that snorers with sleep apnea have a further decrease as lung volume falls.