Clinical characteristics of Japanese children with optic neuritis
Clinical characteristics of Japanese children with optic neuritis
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DOI：
10.1016/j.pediatrneurol.2003.11.011
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发表时间：
2004-07-01
影响因子：
3.8
通讯作者：
Adachi-Usami, E
中科院分区：
文献类型：
--
作者：
Mizota, A;Niimura, M;Adachi-Usami, E
据报道，儿童视神经炎的临床特征与成人不同，并且在不同种族之间存在差异。为了确定日本儿童视神经炎的临床特征，我们检查了1979年1月至2001年12月期间在千叶大学医院眼科诊断为视神经炎的41名儿童的病历。获得了关于性别、发病年龄、偏侧性、初始视力、最终视力、近期感染和免疫接种以及是否存在全身性神经系统疾病（如多发性硬化症或急性播散性脑脊髓炎）的信息。这些发现揭示了儿童视神经炎的临床特征与先前报道的相似。儿童视神经炎病例发展为多发性硬化的比例与欧洲和北美的儿童相似，并且这一比例不低于我们诊所的成人。这些发现可作为日本儿童视神经炎的特征。(C)2004年，Elsevier Inc. All rights reserved.
The clinical characteristics of children with optic neuritis have been reported to be different from that of adults and to vary among different races. To determine the clinical characteristics of Japanese children with optic neuritis, we examined the medical records of 41 children who were diagnosed with optic neuritis at the Department of Ophthalmology of Chiba University Hospital between January 1979 and December 2001. Information on the sex, age of onset, laterality, initial visual acuity, final visual acuity, recent infections and immunizations, and presence of systemic neurologic diseases, such as multiple sclerosis or acute disseminated encephalomyelitis, was obtained. These findings revealed that the clinical features of optic neuritis in children were similar to those reported earlier. The percentage of optic neuritis cases that developed multiple sclerosis in children was similar to that for children in Europe and North America, and this percentage was not lower than that in adults in our clinic. These findings can be taken as the characteristics of optic neuritis of children in Japan. (C) 2004 by Elsevier Inc. All rights reserved.