Organ Procurement and Transplantation in Belgium
Organ Procurement and Transplantation in Belgium
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DOI：
10.1097/tp.0000000000001866
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发表时间：
2017-09-01
期刊：
影响因子：
6.2
通讯作者：
Pirenne, Jacques
中科院分区：
文献类型：
--
作者：
Detry, Olivier;Van Deynse, Dominique;Pirenne, Jacques
比利时的实体器官移植：历史和里程碑比利时是一个拥有1100万居民的联邦制国家(截至2016年)，在移植领域一直非常活跃。临床移植活动始于20世纪60年代初，第一次活体和已故的肾移植。1-5在这些开创性的几年中，比利时在1963年被诊断为脑死亡后进行了第一次死亡器官捐赠(由鲁汶大学的Pr Alexandre)，1，4在1968年进行了肺移植后的第一次长期存活(10个月)(Pr Derom，根特大学)。6比利时移植中心在荷兰莱顿大学的Pr Van Rood的主持下，于1967年直接参与建立了欧洲移植组织。这些努力还包括为肾脏移植候选者和器官捐赠者建立一个数据库，以改进人类白细胞抗原配型。50年后，比利时仍然是欧洲移植基金会的活跃成员，这是一个总部设在莱顿的非营利性组织，目前负责8个欧洲国家的器官分配，总人口近1.35亿人。7比利时移植法比利时移植法的第一个版本于1986年公布，此后稍作修改。8关于已故器官捐赠，比利时立法者决定采用“选择退出”制度，比利时公民可以登记“支持”或“反对”器官捐赠。这项法律没有明确定义用于诊断捐赠者死亡的标准，但提到该标准应为
SOLID ORGAN TRANSPLANTATION IN BELGIUM: HISTORY AND MILESTONES Belgium, a federal country of 11 million inhabitants (as of 2016), has been very active in the field of transplantation. Clinical transplantation activities were initiated in the early 1960s with the first, living and deceased, kidney transplantations. 1-5 During these pioneering years, Belgium was recognized for carrying out the first deceased organ donation after the diagnosis of brain death in 1963 (by Pr Alexandre, University of Leuven), 1, 4 and the first long-term survival (10 months) after lung transplantation in 1968 (Pr Derom, Ghent University). 6 The Belgian transplant centers were directly involved in establishing Eurotransplant in 1967 under the auspices of Pr Van Rood, from the University of Leiden (The Netherlands). Those efforts included also the implementation of a database for kidney transplant candidates and organ donors that improved HLA matching. Fifty years later, Belgium is still an active member of the Eurotransplant Foundation, a nonprofit organization based in Leiden, which is currently in charge of organ allocation in 8 European countries for a total population of nearly 135 million inhabitants. 7THE BELGIAN TRANSPLANTATION LAW The first version of the Belgian transplantation law was published in 1986 and has been slightly modified since. 8 For deceased donation (DD), the Belgian legislator decided for an “opting-out” system, with the possibility for the Belgian citizens to register “for” or “against” organ donation. This law does not explicitly define the criteria to be used to diagnose donor death but mentions that the criteria should be