Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection
Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection
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DOI：
10.1117/1.2904664
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发表时间：
2008-03-01
影响因子：
3.5
通讯作者：
Yang, Changhuei
中科院分区：
文献类型：
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作者：
Han, Shuo;Sarunic, Marinko V.;Yang, Changhuei
我们报道了迄今为止最窄的(21号，820微米直径)手持前向成像光学相干断层扫描(OCT)针状内窥镜，并证明了其用于眼科OCT检查的可行性。探头的设计基于成对角度旋转扫描(PARS)，通过使用两个反向旋转角度抛光的梯度折射率(GRIN)透镜，可以在探头尖端前面形成线性B超图案。该探头虽然体积小，但在0.5帧/S下的数值孔径(NA)为0.22，实验灵敏度为92dB。在猪眼上进行了视网膜成像的可行性测试，其中包括残余玻璃体体液、视网膜和脉络膜的结构特征可以清楚地区分出来。由于其成像质量可与商业OCT系统相媲美，并且与当前的眼科手术标准兼容，该探头有可能在玻璃体视网膜手术(如玻璃体切除)中作为传统白光照明视觉检查的更好替代方案。(C)2008年光学仪器工程师学会。
We report the narrowest to-date (21 gauge, 820-mu m-diam) handheld forward-imaging optical coherence tomography (OCT) needle endoscope and demonstrate its feasibility for ophthalmic OCT inspection. The probe design is based on paired-angle-rotation scanning (PARS), which enables a linear B-scan pattern in front of the probe tip by using two counterrotating angle polished gradient-index (GRIN) lenses. Despite its small size, the probe can provide a numerical apertune (NA) of 0.22 and an experimental sensitivity of 92 dB at 0.5 frame/s. The feasibility of retinal imaging is tested on enucleated ex vivo porcine eyes, where structural features including remnant vitreous humor, retina, and choroid can be clearly distinguished. Due to its imaging quality comparable to a commercial OCT system and compatibility with the current ophthalmic surgery standard, the probe can potentially serve as a better alternative to traditional visual inspection by white light illumination during vitreoretinal surgery (e. g., vitrectomy). (C) 2008 Society of Photo-Optical Instrumentation Engineers.