Health effects associated with sulfuryl fluoride and methyl bromide exposure among structural fumigation workers
Health effects associated with sulfuryl fluoride and methyl bromide exposure among structural fumigation workers
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DOI：
10.2105/ajph.88.12.1774
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发表时间：
1998-12-01
影响因子：
12.7
通讯作者：
Steenland, K
中科院分区：
文献类型：
--
作者：
Calvert, GM;Mueller, CA;Steenland, K
目标.本研究评估了结构熏蒸工人职业接触甲基溴和硫酰氟对健康的影响。方法。对佛罗里达南部的123名结构熏蒸工人和120名参考者进行了横断面研究。包括神经传导、振动、神经行为、视觉、脑功能和肾功能检查。工人接触甲基溴和硫酰氟的中位寿命分别为1.20年和2.85年。在考试前一年的硫酰氟暴露与芯片模式记忆测试和嗅觉测试的性能显着降低。此外，熏蒸工人的圣安娜灵巧测试的优势手和ii非显着较高的腕管综合征的患病率比参照显着降低性能。职业性硫酰氟暴露可能相关。对中枢神经系统有亚临床影响，包括对嗅觉和某些认知功能的影响。然而，没有观察到广泛的模式或认知缺陷，周围神经效应可能是由熏蒸工人经历的人机工程学压力引起的。
Objectives. This study assessed the health effects associated with occupational exposure to methyl bromide and sulfuryl fluoride among structural fumigation workers.Methods. A cross-sectional study of 123 structural fumigation workers and 120 referents in south Florida was conducted. Nerve conduction, vibration, neurobehavioral, visual, olf factory and renal function testing was included.Results. The median lifetime duration of methyl bromide and sulfuryl fluoride exposure among workers was 1.20 years and 2.85 years, respectively. Sulfuryl fluoride exposure over the year preceding examination was associated with significantly reduced performance on die Pattern Memory Test and on olfactory testing. In addition, fumigation workers had significantly reduced performance on the Santa Ana Dexterity Test of the dominant hand and ii nonsignificantly higher prevalence of carpal tunnel syndrome than did the referents.Conclusions. Occupational sulfuryl fluoride exposure may be associated. with subclinical effects on the central nervous system, including effects on olfactory and some cognitive functions. However, no widespread pattern Or cognitive deficits was observed, The peripheral nerve effects were likely caused by ergonomic stresses experienced by the fumigation workers.