Criteria for classifying normal and degenerated lumbar intervertebral disks.
Criteria for classifying normal and degenerated lumbar intervertebral disks.
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DOI：
10.1148/radiology.170.2.2911680
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发表时间：
1989-02
期刊：
影响因子：
19.7
通讯作者：
Shiwei Yu;V. Haughton;L. Sether;K. Ho;M. Wagner
中科院分区：
文献类型：
--
作者：
Shiwei Yu;V. Haughton;L. Sether;K. Ho;M. Wagner
本研究的目的是建立正常和退变腰椎间盘的鉴别标准。本文回顾了31具尸体的冰冻切片和磁共振图像。未成熟髓核，发现年龄2岁;过渡髓核，发现在青少年;和成人髓核与一个完整的纤维环没有撕裂，除了小同心或横向撕裂的纤维环的周边。髓核变色、椎间盘高度降低和信号强度减弱与纤维环放射状撕裂一致。严重退变的髓核也与放射状撕裂或纤维环完全破裂有关。结果表明，椎间盘正常情况下是由未成熟的髓核向成熟的髓核过渡。当纤维环发生放射状撕裂时，髓核内纤维软骨收缩和解体，椎间盘被致密的纤维组织和囊性间隙取代。
The purpose of this study was to develop criteria for distinguishing normal and degenerated lumbar intervertebral disks. Cryomicrotome sections from and magnetic resonance images of 31 cadavers were reviewed. The immature nucleus pulposus, found up to age 2 years; the transitional nucleus pulposus, found in teenagers; and the adult nucleus pulposus were associated with an intact anulus fibrosus without tears except for small concentric or transverse tears in the periphery of the anulus fibrosus. Discoloration of the nucleus pulposus, diminishing disk height, and diminishing signal intensity were associated consistently with a radial tear of the anulus fibrosus. The severely degenerated nucleus pulposus was associated also with a radial tear or complete disruption of the anulus fibrosus. The results suggest that intervertebral disk normally progresses from the immature to the transitional to the adult nucleus pulposus. When a radial tear develops in the anulus there is shrinkage and disorganization of fibrocartilage in the nucleus pulposus and replacement of the disk by dense fibrous tissue and cystic spaces.