A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans

A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans
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DOI：
10.1016/s0167-4781(97)00213-3
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发表时间：
1998-04-29
期刊：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
影响因子：
--
通讯作者：
Lucchesi, J
Lucchesi, J
中科院分区：
其他
文献类型：
--
作者：
Eisen, A;Sattah, M;Lucchesi, J

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我们鉴定了一种新的果蝇蛋白 DBF80，它与小鼠 mDEAD5、酵母 TIF1/2 和哺乳动物 eIF-4A 显着相似。 DBP80 是 DEAD-box 蛋白亚类的成员，包含独特的结构域。 PX(I/R>ILLKR(E/D)EETLEGIKQ(F/Y)(F/Y)，以及七个规范解旋酶结构域。(C) 1998 Elsevier Science B.V.
We have identified a novel Drosophila protein, DBF80, that exhibits significant similarity to mouse mDEAD5, yeast TIF1/2, and mammalian eIF-4A. DBP80 is a member of a subclass of DEAD-box proteins that contains a distinct domain. PX(I/R>ILLKR(E/D)EETLEGIKQ(F/Y)(F/Y), in addition to the seven canonical helicase domains. (C) 1998 Elsevier Science B.V.